Research output per year
Research output per year
Research output
- 1 - 50 out of 1,979 results
Search results
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2025
Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signaling
Leonard, M. R., Jones, D. M., Read, K. A., Pokhrel, S., Tuazon, J. A., Warren, R. T., Yount, J. S. & Oestreich, K. J., Jan 9 2025, In: JCI Insight. 10, 1, e180287.Research output: Contribution to journal › Article › peer-review
Open Access -
A temporary cholesterol-rich diet and bacterial extracellular matrix factors favor Salmonella spp. biofilm formation in the cecum
Cruz-Cruz, A., Schreeg, M. E. & Gunn, J. S., Jan 2025, In: mBio. 16, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Exploiting a type III interferon response to improve chemotherapeutic safety and efficacy
Tilden, S. G., Ricco, M. H., Hemann, E. A. & Anchordoquy, T. J., Jan 1 2025, In: European Journal of Pharmaceutical Sciences. 204, 106974.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
Law, J. D., Gao, Y., Kovvali, S., Thirugnanasambantham, P., Wysocki, V. H., Ahmer, B. M. M. & Gopalan, V., 2025, (Accepted/In press) In: FEBS Open Bio.Research output: Contribution to journal › Article › peer-review
Open Access -
Inactivation of GSK3β by Ser389 phosphorylation prevents thymocyte necroptosis and impacts Tcr repertoire diversity
Valença-Pereira, F., Sheridan, R. M., Riemondy, K. A., Thornton, T., Fang, Q., Barret, B., Paludo, G., Thompson, C., Collins, P., Santiago, M., Oltz, E. & Rincon, M., 2025, (Accepted/In press) In: Cell Death and Differentiation. 10553.Research output: Contribution to journal › Article › peer-review
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In vivo virulence of Staphylococcus aureus in native versus prosthetic left-sided valve endocarditis
Elgharably, H., Claesen, J., Sangwan, N., Etiwy, M., Houghtaling, P., Procop, G. W., Shrestha, N. K., Griffin, B., Navia, J. L., Svensson, L. G., Wozniak, D. J. & Pettersson, G. B., 2025, (Accepted/In press) In: JTCVS Open.Research output: Contribution to journal › Article › peer-review
Open Access -
K27-linked RORγt ubiquitination by Nedd4 potentiates Th17-mediated autoimmunity
Zeng, Q., Guo, H., Tang, N., Renavikar, P. S., Karandikar, N. J., Lovett-Racke, A. E., Racke, M. K., Yan, C., Tang, R., Sinha, S., Ghosh, K., Ryal, J. P., Ouyang, S., Chen, M., Amari, F., Vincenzo, C., Pope, R. M., Li, Y., Yang, H. & Langdon, W. Y. & 1 others, , Dec 2025, In: Journal of biomedical science. 32, 1, 26.Research output: Contribution to journal › Article › peer-review
Open Access -
MtlD as a therapeutic target for intestinal and systemic bacterial infections
Schwieters, A., Cole, A. L., Rego, E., Gao, C., Kebriaei, R., Wysocki, V. H., Gunn, J. S. & Ahmer, B. M. M., Jan 2025, In: Journal of Bacteriology. 207, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Novel oral adjuvant to enhance cytotoxic memory like NK cell responses in HIV vaccine platform
Alles, M., Gunasena, M., Isckarus, C., De Silva, I., Board, S., Mulhern, W., Collins, P., Demberg, T. & Liyanage, N. P. M., Dec 2025, In: npj Vaccines. 10, 1, 5.Research output: Contribution to journal › Article › peer-review
Open Access -
The NAE1-mediated neddylation operates as an essential post-translational modification checkpoint for effector CD8+ T cells
Jin, J., Zhang, R., Li, J., Gao, F., Liao, Z., Yu, Y., Wang, Y., Bucci, D., Xiao, M., Ma, R., Ma, Q., Gao, S., Lio, J., Novais, F., Huang, S. C. C., Zhu, J., Ghoneim, H., Wen, H., Li, Z. & Sun, N. & 1 others, , Mar 11 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 10, e2424061122.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
A bacterial pigment provides cross-species protection from H2O2-and neutrophil-mediated killing
Liu, Y., McQuillen, E. A., Rana, P. S. J. B., Gloag, E. S., Parsek, M. R. & Wozniak, D. J., 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 2, e2312334121.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Age associated susceptibility to SARS-CoV-2 infection in the K18-hACE2 transgenic mouse model
Dwivedi, V., Shivanna, V., Gautam, S., Delgado, J., Hicks, A., Argonza, M., Meredith, R., Turner, J., Martinez-Sobrido, L., Torrelles, J. B. & Kulkarni, V., Jun 2024, In: GeroScience. 46, 3, p. 2901-2913 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Antagonistic Effects of Actin-Specific Toxins on Salmonella Typhimurium Invasion into Mammalian Cells
Heisler, D. B., Kudryashova, E., Hitt, R., Williams, B., Dziejman, M., Gunn, J. & Kudryashov, D. S., Nov 2024, In: Biomolecules. 14, 11, 1428.Research output: Contribution to journal › Article › peer-review
Open Access -
Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
Liang, B., Xing, X., Storts, H., Ye, Z., Claybon, H., Austin, R., Ding, R., Liu, B., Wen, H., Miles, W. O., Fishel, R. & Wang, J. J., 2024, In: Frontiers in Oncology. 14, 1441935.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Autotaxin in encephalitogenic CD4 T cells as a therapeutic target for multiple sclerosis
Petersen-Cherubini, C. L., Murphy, S. P., Xin, M., Liu, Y., Deffenbaugh, J. L., Jahan, I., Rau, C. N., Yang, Y. & Lovett-Racke, A. E., Jan 2024, In: European Journal of Immunology. 54, 1, 2350561.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
BCG immunization induced KLRG1+ NK cells show memory-like responses to mycobacterial and HIV antigens
Gunasena, M., Alles, M., Demberg, T., Mulhern, W. & Liyanage, N. P. M., Sep 1 2024, In: Cellular Immunology. 403-404, 104865.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions
Sacramento, L. A., Amorim, C. F., Lombana, C. G., Beiting, D., Novais, F., Carvalho, L. P., Carvalho, E. M. & Scott, P., May 2024, In: PLoS pathogens. 20, 5 May, e1012211.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
CEMIG: prediction of the cis-regulatory motif using the de Bruijn graph from ATAC-seq
Wang, Y., Li, Y., Wang, C., Jerry Lio, C. W., Ma, Q. & Liu, B., Jan 1 2024, In: Briefings in Bioinformatics. 25, 1, 25.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos
Jones, D. M., Tuazon, J. A., Read, K. A., Leonard, M. R., Pokhrel, S., Sreekumar, B. K., Warren, R. T., Yount, J. S., Collins, P. L. & Oestreich, K. J., Apr 1 2024, In: Journal of Immunology. 212, 7, p. 1129-1141 13 p.Research output: Contribution to journal › Article › peer-review
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Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening
Powell, J. W., Mann, C. A., Toth, P. D., Nolan, S., Steinert, A., Ove, C., Seffernick, J. T., Wozniak, D. J., Kebriaei, R., Lindert, S., Osheroff, N., Yalowich, J. C. & Mitton-Fry, M. J., Aug 8 2024, In: ACS Medicinal Chemistry Letters. 15, 8, p. 1287-1297 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Distinct patterns of SARS-CoV-2 BA.2.87.1 and JN.1 variants in immune evasion, antigenicity, and cell-cell fusion
Li, P., Liu, Y., Faraone, J. N., Hsu, C. C., Chamblee, M., Zheng, Y. M., Carlin, C., Bednash, J. S., Horowitz, J. C., Mallampalli, R. K., Saif, L. J., Oltz, E. M., Jones, D., Li, J., Gumina, R. J. & Liu, S. L., May 2024, In: mBio. 15, 5Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease
Daily, K. P., Badr, A., Eltobgy, M., Estfanous, S., Whitham, O., Tan, M. H., Carafice, C., Krause, K., McNamara, A., Hamilton, K., Houle, S., Gupta, S., Gupta, G. A., Madhu, S., Fitzgerald, J., Saadey, A. A., Laster, B., Yan, P., Webb, A. & Zhang, X. & 4 others, , Feb 8 2024, In: Alzheimer's Research and Therapy. 16, 1, p. 29 29.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Dysregulated autotaxin expression by T cells in multiple sclerosis
Petersen-Cherubini, C. L., Liu, Y., Deffenbaugh, J. L., Murphy, S. P., Xin, M., Rau, C. N., Yang, Y. & Lovett-Racke, A. E., Feb 15 2024, In: Journal of Neuroimmunology. 387, 578282.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging
Headley, C. A., Gautam, S., Olmo-Fontanez, A., Garcia-Vilanova, A., Dwivedi, V., Akhter, A., Schami, A., Chiem, K., Ault, R., Zhang, H., Cai, H., Whigham, A., Delgado, J., Hicks, A., Tsao, P. S., Gelfond, J., Martinez-Sobrido, L., Wang, Y., Torrelles, J. B. & Turner, J., Feb 2 2024, In: Advanced Science. 11, 5, 2303664.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs
Xia, B., Chen, H., Taleb, S. J., Xi, X., Shaheen, N., Baoyinna, B., Soni, S., Mebratu, Y. A., Yount, J., Zhao, J. & Zhao, Y., Oct 2024, In: American Journal of Physiology - Heart and Circulatory Physiology. 327, 4, p. H937-H946Research output: Contribution to journal › Article › peer-review
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Functional role of the biofilm regulator CsgD in Salmonella enterica sv. Typhi
González, J. F., Laipply, B., Sadowski, V. A., Price, M. & Gunn, J. S., 2024, In: Frontiers in Cellular and Infection Microbiology. 14, 1478488.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation
Speaks, S., McFadden, M. I., Zani, A., Solstad, A., Leumi, S., Roettger, J. E., Kenney, A. D., Bone, H., Zhang, L., Denz, P. J., Eddy, A. C., Amer, A. O., Robinson, R. T., Cai, C., Ma, J., Hemann, E. A., Forero, A. & Yount, J. S., Dec 2024, In: Nature Communications. 15, 1, 2751.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Genital epithelial barrier function is conserved by intravaginal rings releasing etonogestrel and ethinyl estradiol
Liu, M., Vicetti Miguel, R. D., Quispe Calla, N. E., Aceves, K. M., Fritts, L., Miller, C. J., Moss, J. A., Baum, M. M. & Cherpes, T. L., Jan 2 2024, In: Tissue Barriers. 12, 1, p. 2186672 2186672.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species
Natrajan, M. S., Hall, J. M., Weigand, M. R., Peng, Y., Williams, M. M., Momin, M., Damron, F. H., Dubey, P., Tondella, M. L. & Pawloski, L. C., Jan 2024, In: Microbiology spectrum. 12, 1Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Gut microbiota carbon and sulfur metabolisms support Salmonella infections
Leleiwi, I., Kokkinias, K., Kim, Y., Baniasad, M., Shaffer, M., Sabag-Daigle, A., Daly, R. A., Flynn, R. M., Wysocki, V., Ahmer, B. M. M., Borton, M. A. & Wrighton, K. C., Jan 1 2024, In: ISME Journal. 18, 1, wrae187.Research output: Contribution to journal › Article › peer-review
Open Access -
Human alveolar lining fluid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells
Olmo-Fontánez, A. M., Scordo, J. M., Schami, A., Garcia-Vilanova, A., Pino, P. A., Hicks, A., Mishra, R., Jose Maselli, D., Peters, J. I., Restrepo, B. I., Nargan, K., Naidoo, T., Clemens, D. L., Steyn, A. J. C., Thacker, V. V., Turner, J., Schlesinger, L. S. & Torrelles, J. B., Apr 2024, In: Mucosal Immunology. 17, 2, p. 155-168 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Identification of new SdiA regulon members of Escherichia coli, Enterobacter cloacae, and Salmonella enterica serovars Typhimurium and Typhi
Schwieters, A. & Ahmer, B. M. M., Dec 2024, In: Microbiology spectrum. 12, 12Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN
Solstad, A. D., Denz, P. J., Kenney, A. D., Mahfooz, N. S., Speaks, S., Gong, Q., Robinson, R. T., Long, M. E., Forero, A., Yount, J. S. & Hemann, E. A., May 21 2024, In: JCI Insight. 9, 13, e171830.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants
Qu, P., Xu, K., Faraone, J. N., Goodarzi, N., Zheng, Y. M., Carlin, C., Bednash, J. S., Horowitz, J. C., Mallampalli, R. K., Saif, L. J., Oltz, E. M., Jones, D., Gumina, R. J. & Liu, S. L., Feb 1 2024, In: Cell. 187, 3, p. 585-595.e6Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes
Vesely, M. D., Kidacki, M., Gaule, P., Gupta, S., Chan, N. N. N., Han, X., Yeung, J. T. & Chen, L., Jan 2024, In: Journal of Investigative Dermatology. 144, 1, p. 106-115.e4Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Impact of the elderly lung mucosa on Mycobacterium tuberculosis transcriptional adaptation during infection of alveolar epithelial cells
Olmo-Fontánez, A. M., Allué-Guardia, A., Garcia-Vilanova, A., Glenn, J., Wang, S. H., Merritt, R. E., Schlesinger, L. S., Turner, J., Wang, Y. & Torrelles, J. B., Dec 2024, In: Microbiology spectrum. 12, 12Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Inhibition of Bruton’s tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors
Schwarz, E., Benner, B., Wesolowski, R., Quiroga, D., Good, L., Sun, S. H., Savardekar, H., Li, J., Jung, K. J., Duggan, M. C., Lapurga, G., Shaffer, J., Scarberry, L., Konda, B., Verschraegen, C., Kendra, K., Shah, M., Rupert, R., Monk, P. & Shah, H. A. & 12 others, , Nov 8 2024, In: JCI Insight. 9, 21, e169927.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of O-GlcNAc transferase activates type I interferon-dependent antitumor immunity by bridging cGAS-STING pathway
Chen, J., Zhao, B., Dong, H., Li, T., Cheng, X., Gong, W., Wang, J., Zhang, J., Xin, G., Yu, Y., Lei, Y. L., Black, J. D., Li, Z. & Wen, H., Oct 4 2024, In: eLife. 13Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Innate immune control of influenza virus interspecies adaptation via IFITM3
Denz, P. J., Speaks, S., Kenney, A. D., Eddy, A. C., Papa, J. L., Roettger, J., Scace, S. C., Rubrum, A., Hemann, E. A., Forero, A., Webby, R. J., Bowman, A. S. & Yount, J. S., Dec 2024, In: Nature Communications. 15, 1, 9375.Research output: Contribution to journal › Article › peer-review
Open Access -
Locus folding mechanisms determine modes of antigen receptor gene assembly
Allyn, B. M., Hayer, K. E., Oyeniran, C., Nganga, V., Lee, K., Mishra, B., Sacan, A., Oltz, E. M. & Bassing, C. H., Feb 5 2024, In: Journal of Experimental Medicine. 221, 2, e20230985.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
MarsGT: Multi-omics analysis for rare population inference using single-cell graph transformer
Wang, X., Duan, M., Li, J., Ma, A., Xin, G., Xu, D., Li, Z., Liu, B. & Ma, Q., Dec 2024, In: Nature Communications. 15, 1, 338.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection
De, M., Serpa, G., Zuiker, E., Hisert, K. B., Liles, W. C., Manicone, A. M., Hemann, E. A. & Long, M. E., Jan 29 2024, In: Frontiers in Cellular and Infection Microbiology. 14, p. 1275940 1275940.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Metabolically active neutrophils represent a permissive niche for Mycobacterium tuberculosis
Andrews, J. T., Zhang, Z., Prasad, G. V. R. K., Huey, F., Nazarova, E. V., Wang, J., Ranaraja, A., Weinkopff, T., Li, L. X., Mu, S., Birrer, M. J., Huang, S. C. C., Zhang, N., Argüello, R. J., Philips, J. A., Mattila, J. T. & Huang, L., Oct 2024, In: Mucosal Immunology. 17, 5, p. 825-842 18 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Microglia-targeted inhibition of miR-17 via mannose-coated lipid nanoparticles improves pathology and behavior in a mouse model of Alzheimer's disease
Badr, A., Daily, K. P., Eltobgy, M., Estfanous, S., Tan, M. H., Chun-Tien Kuo, J., Whitham, O., Carafice, C., Gupta, G., Amer, H. M., Shamseldin, M. M., Yousif, A., Deems, N. P., Fitzgerald, J., Yan, P., Webb, A., Zhang, X., Pietrzak, M., Ghoneim, H. E. & Dubey, P. & 4 others, , Jul 2024, In: Brain, Behavior, and Immunity. 119, p. 919-944 26 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
MicroRNAs targeting TGF-β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function
Rau, C. N., Severin, M. E., Lee, P. W., Deffenbaugh, J. L., Liu, Y., Murphy, S. P., Petersen-Cherubini, C. L. & Lovett-Racke, A. E., Jun 2024, In: European Journal of Immunology. 54, 6, 2350548.Research output: Contribution to journal › Article › peer-review
Open Access -
Mitochondrial Transplantation Promotes Protective Effector and Memory CD4+ T Cell Response During Mycobacterium Tuberculosis Infection and Diminishes Exhaustion and Senescence in Elderly CD4+ T cells
Headley, C. A., Gautam, S., Olmo-Fontanez, A., Garcia-Vilanova, A., Dwivedi, V., Schami, A., Weintraub, S., Tsao, P. S., Torrelles, J. B. & Turner, J., Sep 25 2024, In: Advanced Science. 11, 36, 2401077.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
mRNA vaccines against SARS-CoV-2 induce divergent antigen-specific T-cell responses in patients with lung cancer
Song, N. J., Chakravarthy, K. B., Jeon, H., Bolyard, C., Reynolds, K., Weller, K. P., Reisinger, S., Wang, Y., Li, A., Jiang, S., Ma, Q., Barouch, D. H., Rubinstein, M. P., Shields, P. G., Oltz, E. M., Chung, D. & Li, Z., Jan 4 2024, In: Journal for ImmunoTherapy of Cancer. 12, 1, e007922.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Neutralization escape, infectivity, and membrane fusion of JN.1-derived SARS-CoV-2 SLip, FLiRT, and KP.2 variants
Li, P., Faraone, J. N., Hsu, C. C., Chamblee, M., Zheng, Y. M., Carlin, C., Bednash, J. S., Horowitz, J. C., Mallampalli, R. K., Saif, L. J., Oltz, E. M., Jones, D., Li, J., Gumina, R. J., Xu, K. & Liu, S. L., Aug 27 2024, In: Cell Reports. 43, 8, 114520.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Neutrophil extracellular traps induced by chemotherapy inhibit tumor growth in murine models of colorectal cancer
Li, Y., Wu, S., Zhao, Y., Dinh, T., Jiang, D., Selfridge, J. E., Myers, G., Wang, Y., Zhao, X., Tomchuck, S., Dubyak, G., Lee, R. T., Estfan, B., Shapiro, M., Kamath, S., Mohamed, A., Huang, S. C. C., Huang, A. Y., Conlon, R. & Krishnamurthi, S. & 5 others, , Mar 1 2024, In: Journal of Clinical Investigation. 134, 5, e175031.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Neutrophil-mediated hypoxia drives pathogenic CD8+ T cell responses in cutaneous leishmaniasis
Fowler, E. A., Amorim, C. F., Mostacada, K., Yan, A., Sacramento, L. A., Stanco, R. A., Hales, E. D. S., Varkey, A., Zong, W., Wu, G. D., de Oliveira, C. I., Collins, P. L. & Novais, F. O., Jul 15 2024, In: Journal of Clinical Investigation. 134, 14, e177992.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations