Amanda E. Toland

2024

Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study

Tjader, N. P., Beer, A. J., Ramroop, J., Tai, M. C., Ping, J., Gandhi, T., Dauch, C., Neuhausen, S. L., Ziv, E., Sotelo, N., Ghanekar, S., Meadows, O., Paredes, M., Gillespie, J. L., Aeilts, A. M., Hampel, H., Zheng, W., Jia, G., Hu, Q. & Wei, L. & 13 others, Liu, S., Ambrosone, C. B., Palmer, J. R., Carpten, J. D., Yao, S., Stevens, P., Ho, W. K., Pan, J. W., Fadda, P., Huo, D., Teo, S. H., McElroy, J. P. & Toland, A. E., Jun 1 2024, In: Cancer research communications. 4, 6, p. 1597-1608 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses

Papadimitriou, N., Qu, C., Harrison, T. A., Bever, A. M., Martin, R. M., Tsilidis, K. K., Newcomb, P. A., Thibodeau, S. N., Newton, C. C., Um, C. Y., Obón-Santacana, M., Moreno, V., Brenner, H., Mandic, M., Chang-Claude, J., Hoffmeister, M., Pellatt, A. J., Schoen, R. E., Harlid, S. & Ogino, S. & 33 others, Ugai, T., Buchanan, D. D., Lynch, B. M., Gruber, S. B., Cao, Y., Hsu, L., Huyghe, J. R., Lin, Y., Steinfelder, R. S., Sun, W., Van Guelpen, B., Zaidi, S. H., Toland, A. E., Berndt, S. I., Huang, W. Y., Aglago, E. K., Drew, D. A., French, A. J., Georgeson, P., Giannakis, M., Hullar, M., Nowak, J. A., Thomas, C. E., Le Marchand, L., Cheng, I., Gallinger, S., Jenkins, M. A., Gunter, M. J., Campbell, P. T., Peters, U., Song, M., Phipps, A. I. & Murphy, N., Mar 2024, In: EBioMedicine. 101, 105010.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Clinical features of prostate cancer by polygenic risk score

Spears, C., Xu, M., Shoben, A., Dason, S., Toland, A. E. & Byrne, L., Nov 2024, In: Familial Cancer. 23, 4, p. 499-505 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature

Thomas, C. E., Georgeson, P., Qu, C., Steinfelder, R. S., Buchanan, D. D., Song, M., Harrison, T. A., Um, C. Y., Hullar, M. A., Jenkins, M. A., Van Guelpen, B., Lynch, B. M., Melaku, Y. A., Huyghe, J. R., Aglago, E. K., Berndt, S. I., Boardman, L. A., Campbell, P. T., Cao, Y. & Chan, A. T. & 25 others, Drew, D. A., Figueiredo, J. C., French, A. J., Giannakis, M., Goode, E. L., Gruber, S. B., Gsur, A., Gunter, M. J., Hoffmeister, M., Hsu, L., Huang, W. Y., Moreno, V., Murphy, N., Newcomb, P. A., Newton, C. C., Nowak, J. A., Obón-Santacana, M., Ogino, S., Sun, W., Toland, A. E., Trinh, Q. M., Ugai, T., Zaidi, S. H., Peters, U. & Phipps, A. I., Apr 1 2024, In: Cancer Epidemiology Biomarkers and Prevention. 33, 4, p. OF1-OF13

Research output: Contribution to journal › Article › peer-review

Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Chen, Z., Guo, X., Tao, R., Huyghe, J. R., Law, P. J., Fernandez-Rozadilla, C., Ping, J., Jia, G., Long, J., Li, C., Shen, Q., Xie, Y., Timofeeva, M. N., Thomas, M., Schmit, S. L., Díez-Obrero, V., Devall, M., Moratalla-Navarro, F., Fernandez-Tajes, J. & Palles, C. & 185 others, Sherwood, K., Briggs, S. E. W., Svinti, V., Donnelly, K., Farrington, S. M., Blackmur, J., Vaughan-Shaw, P. G., Shu, X. O., Lu, Y., Broderick, P., Studd, J., Harrison, T. A., Conti, D. V., Schumacher, F. R., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J. L., Jenkins, M. A., Win, A. K., Pai, R. K., Figueiredo, J. C., Haile, R. W., Gallinger, S., Woods, M. O., Newcomb, P. A., Duggan, D., Cheadle, J. P., Kaplan, R., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, J. P., Jousilahti, P., Knekt, P., Aaltonen, L. A., Rissanen, H., Pukkala, E., Eriksson, J. G., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Männistö, S., Albanes, D., Weinstein, S. J., Ruiz-Narvaez, E., Palmer, J. R., Buchanan, D. D., Platz, E. A., Visvanathan, K., Ulrich, C. M., Siegel, E., Brezina, S., Gsur, A., Campbell, P. T., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M. L., Potter, J. D., Tsilidis, K. K., Schulze, M. B., Gunter, M. J., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Bishop, D. T., Giles, G. G., Southey, M. C., Idos, G. E., McDonnell, K. J., Abu-Ful, Z., Greenson, J. K., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T. O., van Guelpen, B., Hudson, T. J., Hampel, H., Pearlman, R., Berndt, S. I., Hayes, R. B., Martinez, M. E., Thomas, S. S., Pharoah, P. D. P., Larsson, S. C., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K. F., Pugh, E., Shelford, T., Chan, A. T., Cruz-Correa, M., Lindblom, A., Hunter, D. J., Joshi, A. D., Schafmayer, C., Scacheri, P. C., Kundaje, A., Schoen, R. E., Hampe, J., Stadler, Z. K., Vodicka, P., Vodickova, L., Vymetalkova, V., Edlund, C. K., Gauderman, W. J., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S. J., van Duijnhoven, F., Feskens, E. J. M., Sakoda, L. C., Gago-Dominguez, M., Wolk, A., Pardini, B., FitzGerald, L. M., Lee, S. C., Ogino, S., Bien, S. A., Kooperberg, C., Li, C. I., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Yamaji, T., Sawada, N., Iwasaki, M., Le Marchand, L., Wu, A. H., Qu, C., McNeil, C. E., Coetzee, G., Hayward, C., Deary, I. J., Harris, S. E., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Lau, K. S., Zhao, H., Hsu, L., Cai, Q., Dunlop, M. G., Gruber, S. B., Houlston, R. S., Moreno, V., Casey, G., Peters, U., Tomlinson, I. & Zheng, W., Dec 2024, In: Nature Communications. 15, 1, 3557.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Metabolic trade-offs in Neonatal sepsis triggered by TLR4 and TLR1/2 ligands result in unique dysfunctions in neural breathing circuits

Joana Alves, M., Browe, B. M., Carolina Rodrigues Dias, A., Torres, J. M., Zaza, G., Bangudi, S., Blackburn, J., Wang, W., de Araujo Fernandes- Junior, S., Fadda, P., Toland, A., Baer, L. A., Stanford, K. I., Czeisler, C., Garcia, A. J. & Javier Otero, J., Jul 2024, In: Brain, Behavior, and Immunity. 119, p. 333-350 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Presumed Pathogenic Germ Line and Somatic Variants in African American Thyroid Cancer

Hurst, Z. A., Liyanarachchi, S., Brock, P., He, H., Nabhan, F., Veloski, C., Toland, A. E., Ringel, M. D. & Jhiang, S. M., Mar 1 2024, In: Thyroid. 34, 3, p. 378-387 10 p.

Research output: Contribution to journal › Article › peer-review

2023

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry

NBCS Collaborators, CTS Consortium & ABCTB Investigators, Dec 2023, In: Genome medicine. 15, 1, 7.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Schmit, S., Díez-Obrero, V., Hsu, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S., Svinti, V., Donnelly, K., Farrington, S., Blackmur, J., Vaughan-Shaw, P., Shu, X. O., Long, J. & Cai, Q. & 190 others, Guo, X., Lu, Y., Broderick, P., Studd, J., Huyghe, J., Harrison, T., Conti, D., Dampier, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. O., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Duggan, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, L. P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Hunter, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., Jan 2023, In: Nature Genetics. 55, 1, p. 89-99 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

Development of a web-based, theory-guided narrative intervention for women at elevated risk for breast cancer

Katz, M. L., Senter, L., Reiter, P. L., Emerson, B., Ennis, A. C., Shane-Carson, K. P., Aeilts, A., Cassingham, H. R., Schnell, P. M., Agnese, D. M., Toland, A. E. & Sweet, K., Jan 2023, In: Patient Education and Counseling. 106, p. 163-169 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

Stolarova, L., Kleiblova, P., Zemankova, P., Stastna, B., Janatova, M., Soukupova, J., Achatz, M. I., Ambrosone, C., Apostolou, P., Arun, B. K., Auer, P., Barnard, M., Bertelsen, B., Japan, B., Blok, M. J., Boddicker, N., Brunet, J., Burnside, E. S., Calvello, M. & Campbell, I. & 92 others, Chan, S. H., Chen, F., Chiang, J. B., Coppa, A., Cortesi, L., Crujeiras-González, A., Czecanca, C., De Leeneer, K., De Putter, R., DePersia, A., Devereux, L., Domchek, S., Efremidis, A., Engel, C., Ernst, C., Evans, G. D. R., Feliubadaló, L., Fostira, F., Fuentes-Ríos, O., Gómez-García, E. B., González, S., Haiman, C., van Overeem Hansen, T., Hauke, J., Hodge, J., Hu, C., Huang, H., Binte Ishak, N. D., Iwasaki, Y., Konstantopoulou, I., Kraft, P., Lacey, J., Lázaro, C., Li, N., Lim, W. K., Lindstrom, S., Lori, A., Martinez, E., Martins, A., Matsuda, K., Matullo, G., McInerny, S., Michailidou, K., Montagna, M., Monteiro, A. N. A., Mori, L., Nathanson, K., Neuhausen, S. L., Nevanlinna, H., Olson, J. E., Palmer, J., Pasini, B., Patel, A., Piane, M., Poppe, B., Radice, P., Renieri, A., Resta, N., Richardson, M. E., Rosseel, T., Ruddy, K. J., Santamariña, M., Dos Santos, E. S., Teras, L., Toland, A. E., Trentham-Dietz, A., Vachon, C. M., Volk, A. E., Weber-Lassalle, N., Weitzel, J. N., Wiesmuller, L., Winham, S., Yadav, S., Yannoukakos, D., Yao, S., Zampiga, V., Zethoven, M., Zhang, Z. W., Zima, T., Spurdle, A. B., Vega, A., Rossing, M., Valle, J. D., De Nicolo, A., Hahnen, E., Claes, K. B. M., Ngeow, J., Momozawa, Y., James, P. A., Couch, F. J., Macurek, L. & Kleibl, Z., Aug 15 2023, In: Clinical Cancer Research. 29, 16, p. 3037-3050 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel

NBCS Collaborators, Dec 1 2023, In: Journal of Medical Genetics. 60, 12, p. 1186-1197 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Genetic counseling and testing for females at elevated risk for breast cancer: Protocol for the randomized controlled trial of the Know Your Risk intervention

Sweet, K., Reiter, P. L., Schnell, P. M., Senter, L., Shane-Carson, K. P., Aeilts, A., Cooper, J., Spears, C., Brown, J., Toland, A. E., Agnese, D. M. & Katz, M. L., Oct 2023, In: Contemporary Clinical Trials. 133, 107323.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Glioblastoma pseudoprogression and true progression reveal spatially variable transcriptional differences

James Cancer Center Integrated Neuro-Oncology Team, Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 192.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases

Ugai, T., Haruki, K., Harrison, T. A., Cao, Y., Qu, C., Chan, A. T., Campbell, P. T., Akimoto, N., Berndt, S., Brenner, H., Buchanan, D. D., Chang-Claude, J., Fujiyoshi, K., Gallinger, S. J., Gunter, M. J., Hidaka, A., Hoffmeister, M., Hsu, L., Jenkins, M. A. & Milne, R. L. & 21 others, Moreno, V., Newcomb, P. A., Nishihara, R., Pai, R. K., Sakoda, L. C., Slattery, M. L., Sun, W., Amitay, E. L., Alwers, E., Thibodeau, S. N., Toland, A. E., Van Guelpen, B., Woods, M. O., Zaidi, S. H., Potter, J. D., Giannakis, M., Song, M., Nowak, J. A., Phipps, A. I., Peters, U. & Ogino, S., Apr 1 2023, In: American Journal of Gastroenterology. 118, 4, p. 712-726 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

CZECANCA Consortium, The Consortium of Investigators of Modifiers of BRCA1/2, Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium, HEBON Investigators, GEMO Study Collaborators & AOCS Group, Jun 29 2023, In: British Journal of Cancer. 128, 12, p. 2283-2294 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Patient Understanding of Tumor Genomic Testing: A Quality Improvement Effort

Senter, L., Veney, D., Surplus, T., Haynam, M., Adams, E. J., Hampel, H., Toland, A. E., Presley, C. J., Padamsee, T. J., Lee, C. N., Hovick, S. R. & Stover, D. G., Jan 1 2023, In: JCO Oncology Practice. 19, 1, p. E8-E14

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

Ugai, T., Akimoto, N., Haruki, K., Harrison, T. A., Cao, Y., Qu, C., Chan, A. T., Campbell, P. T., Berndt, S. I., Buchanan, D. D., Cross, A. J., Diergaarde, B., Gallinger, S. J., Gunter, M. J., Harlid, S., Hidaka, A., Hoffmeister, M., Brenner, H., Chang-Claude, J. & Hsu, L. & 26 others, Jenkins, M. A., Lin, Y., Milne, R. L., Moreno, V., Newcomb, P. A., Nishihara, R., Obon-Santacana, M., Pai, R. K., Sakoda, L. C., Schoen, R. E., Slattery, M. L., Sun, W., Amitay, E. L., Alwers, E., Thibodeau, S. N., Toland, A. E., Van Guelpen, B., Zaidi, S. H., Potter, J. D., Meyerhardt, J. A., Giannakis, M., Song, M., Nowak, J. A., Peters, U., Phipps, A. I. & Ogino, S., Mar 2023, In: Journal of Gastroenterology. 58, 3, p. 229-245 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Turning the Page on Breast Cancer in Ohio: Lessons learned from implementing a multilevel intervention to reduce breast cancer mortality among Black women

Padamsee, T. J., Stover, D. G., Tarver, W. L., Washington, C. M., Baltic, R. D., DeGraffinreid, C. R., Whiting, C. R. B., Rumano, R., Lee, C. N., Nolan, T., Oppong, B., Obeng-Gyasi, S., Toland, A. E., Bernardo, B., Doll, H. L. & Paskett, E. D., Sep 2023, In: Cancer. 129, p. 3114-3127 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2022

Association between germline variants and somatic mutations in colorectal cancer

Barfield, R., Qu, C., Steinfelder, R. S., Zeng, C., Harrison, T. A., Brezina, S., Buchanan, D. D., Campbell, P. T., Casey, G., Gallinger, S., Giannakis, M., Gruber, S. B., Gsur, A., Hsu, L., Huyghe, J. R., Moreno, V., Newcomb, P. A., Ogino, S., Phipps, A. I. & Slattery, M. L. & 7 others, Thibodeau, S. N., Trinh, Q. M., Toland, A. E., Hudson, T. J., Sun, W., Zaidi, S. H. & Peters, U., Dec 2022, In: Scientific Reports. 12, 1, 10207.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

Barnes, D. R., Silvestri, V., Leslie, G., McGuffog, L., Dennis, J., Yang, X., Adlard, J., Agnarsson, B. A., Ahmed, M., Aittomaki, K., Andrulis, I. L., Arason, A., Arnold, N., Auber, B., Azzollini, J., Balmana, J., Barkardottir, R. B., Barrowdale, D., Barwell, J. & Belotti, M. & 144 others, Benitez, J., Berthet, P., Boonen, S. E., Borg, A., Bozsik, A., Brady, A. F., Brennan, P., Brewer, C., Brunet, J., Bucalo, A., Buys, S. S., Caldes, T., Caligo, M. A., Campbell, I., Cassingham, H., Christensen, L. L., Cini, G., Claes, K. B. M., Cook, J., Coppa, A., Cortesi, L., Damante, G., Darder, E., Davidson, R., De La Hoya, M., De Leeneer, K., De Putter, R., Del Valle, J., Diez, O., Ding, Y. C., Domchek, S. M., Donaldson, A., Eason, J., Eeles, R., Engel, C., Evans, D. G., Feliubadalo, L., Fostira, F., Frone, M., Frost, D., Gallagher, D., Gehrig, A., Giraud, S., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gregory, H., Gross, E., Hahnen, E., Hamann, U., Hansen, T. V. O., Hanson, H., Hentschel, J., Horvath, J., Izatt, L., Izquierdo, A., James, P. A., Janavicius, R., Jensen, U. B., Johannsson, O. T., John, E. M., Kramer, G., Kroeldrup, L., Kruse, T. A., Lautrup, C., Lazaro, C., Lesueur, F., Lopez-Fernandez, A., Mai, P. L., Manoukian, S., Matrai, Z., Matricardi, L., Maxwell, K. N., Mebirouk, N., Meindl, A., Montagna, M., Monteiro, A. N., Morrison, P. J., Muranen, T. A., Murray, A., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Nguyen-Dumont, T., Niederacher, D., Olah, E., Olopade, O. I., Palli, D., Parsons, M. T., Pedersen, I. S., Peissel, B., Perez-Segura, P., Peterlongo, P., Petersen, A. H., Pinto, P., Porteous, M. E., Pottinger, C., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Robson, M., Rogers, M. T., Rønlund, K., Rump, A., Sanchez De Abajo, A. M., Shah, P. D., Sharif, S., Side, L. E., Singer, C. F., Stadler, Z., Steele, L., Stoppa-Lyonnet, D., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teule, A., Thull, D. L., Tischkowitz, M., Toland, A. E., Tommasi, S., Toss, A., Trainer, A. H., Tripathi, V., Valentini, V., Van Asperen, C. J., Venturelli, M., Viel, A., Vijai, J., Walker, L., Wang-Gohrke, S., Wappenschmidt, B., Whaite, A., Zanna, I., Offit, K., Thomassen, M., Couch, F. J., Schmutzler, R. K., Simard, J., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C. & Ottini, L., Jan 1 2022, In: Journal of the National Cancer Institute. 114, 1, p. 109-122 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants

Li, S., Silvestri, V., Leslie, G., Rebbeck, T. R., Neuhausen, S. L., Hopper, J. L., Nielsen, H. R., Lee, A., Yang, X., Mcguffog, L., Parsons, M. T., Andrulis, I. L., Arnold, N., Belotti, M., Borg, Å., Buecher, B., Buys, S. S., Caputo, S. M., Chung, W. K. & Colas, C. & 82 others, Colonna, S. V., Cook, J., Daly, M. B., De La Hoya, M., De Pauw, A., Delhomelle, H., Eason, J., Engel, C., Evans, D. G., Faust, U., Fehm, T. N., Fostira, F., Fountzilas, G., Frone, M., Garcia-Barberan, V., Garre, P., Gauthier-Villars, M., Gehrig, A., Glendon, G., Goldgar, D. E., Golmard, L., Greene, M. H., Hahnen, E., Hamann, U., Hanson, H., Hassan, T., Hentschel, J., Horvath, J., Izatt, L., Janavicius, R., Jiao, Y., John, E. M., Karlan, B. Y., Kim, S. W., Konstantopoulou, I., Kwong, A., Laugé, A., Lee, J. W., Lesueur, F., Mebirouk, N., Meindl, A., Mouret-Fourme, E., Musgrave, H., Ngeow Yuen Yie, J., Niederacher, D., Park, S. K., Pedersen, I. S., Ramser, J., Ramus, S. J., Rantala, J., Rashid, M. U., Reichl, F., Ritter, J., Rump, A., Santamariña, M., Saule, C., Schmidt, G., Schmutzler, R. K., Senter, L., Shariff, S., Singer, C. F., Southey, M. C., Stoppa-Lyonnet, D., Sutter, C., Tan, Y., Teo, S. H., Terry, M. B., Thomassen, M., Tischkowitz, M., Toland, A. E., Torres, D., Vega, A., Wagner, S. A., Wang-Gohrke, S., Wappenschmidt, B., Weber, B. H. F., Yannoukakos, D., Spurdle, A. B., Easton, D. F., Chenevix-Trench, G., Ottini, L. & Antoniou, A. C., May 10 2022, In: Journal of Clinical Oncology. 40, 14, p. 1529-1541 13 p.

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145 Scopus citations

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

GEMO Study Collaborators, EMBRACE Collaborators, SWE-BRCA Investigators, kConFab Investigators & HEBON Investigators, Dec 2022, In: Communications biology. 5, 1, 1061.

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Open Access

6 Scopus citations

Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases

Harlid, S., Van Guelpen, B., Qu, C., Gylling, B., Aglago, E. K., Amitay, E. L., Brenner, H., Buchanan, D. D., Campbell, P. T., Cao, Y., Chan, A. T., Chang-Claude, J., Drew, D. A., Figueiredo, J. C., French, A. J., Gallinger, S., Giannakis, M., Giles, G. G., Gunter, M. J. & Hoffmeister, M. & 22 others, Hsu, L., Jenkins, M. A., Lin, Y., Moreno, V., Murphy, N., Newcomb, P. A., Newton, C. C., Nowak, J. A., Obón-Santacana, M., Ogino, S., Potter, J. D., Song, M., Steinfelder, R. S., Sun, W., Thibodeau, S. N., Toland, A. E., Ugai, T., Um, C. Y., Woods, M. O., Phipps, A. I., Harrison, T. & Peters, U., Aug 1 2022, In: International Journal of Cancer. 151, 3, p. 348-360 13 p.

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Open Access

3 Scopus citations

Differences in somatic TP53 mutation type in breast tumors by race and receptor status

Pollock, N. C., Ramroop, J. R., Hampel, H., Troester, M. A., Conway, K., Hu, J. J., Freudenheim, J. L., Olopade, O. I., Huo, D., Ziv, E., Neuhausen, S. L., Stevens, P., McElroy, J. P. & Toland, A. E., Apr 2022, In: Breast Cancer Research and Treatment. 192, 3, p. 639-648 10 p.

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Open Access

14 Scopus citations

Genetic analysis of a malignant meningioma and associated metastases

Huntoon, K., Yilmaz, A. S., Pietrzak, M., Chen, X., Yan, P., Toland, A. E. & Elder, J. B., May 2022, In: Acta Neurochirurgica. 164, 5, p. 1401-1405 5 p.

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4 Scopus citations

Genetic polymorphism in Methylenetetrahydrofolate Reductase chloride transport protein 6 (MTHFR CLCN6) gene is associated with keratinocyte skin cancer in a cohort of renal transplant recipients

Griffin, L., Ho, L., Akhurst, R. J., Arron, S. T., Boggs, J. M. E., Conlon, P., O’Kelly, P., Toland, A. E., Epstein, E. H., Balmain, A., Bastian, B. C., Moloney, F. J., Murphy, G. M. & Laing, M. E., Jun 2022, In: Skin Health and Disease. 2, 2, e95.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures

Georgeson, P., Harrison, T. A., Pope, B. J., Zaidi, S. H., Qu, C., Steinfelder, R. S., Lin, Y., Joo, J. E., Mahmood, K., Clendenning, M., Walker, R., Amitay, E. L., Berndt, S. I., Brenner, H., Campbell, P. T., Cao, Y., Chan, A. T., Chang-Claude, J., Doheny, K. F. & Drew, D. A. & 32 others, Figueiredo, J. C., French, A. J., Gallinger, S., Giannakis, M., Giles, G. G., Gsur, A., Gunter, M. J., Hoffmeister, M., Hsu, L., Huang, W. Y., Limburg, P., Manson, J. A. E., Moreno, V., Nassir, R., Nowak, J. A., Obón-Santacana, M., Ogino, S., Phipps, A. I., Potter, J. D., Schoen, R. E., Sun, W., Toland, A. E., Trinh, Q. M., Ugai, T., Macrae, F. A., Rosty, C., Hudson, T. J., Jenkins, M. A., Thibodeau, S. N., Winship, I. M., Peters, U. & Buchanan, D. D., Dec 2022, In: Nature Communications. 13, 1, 3254.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Polygenic risk modeling for prediction of epithelial ovarian cancer risk

GEMO Study Collaborators, GC-HBOC Study Collaborators, EMBRACE Collaborators, OPAL study group, AOCS Group, kConFab Investigators, HEBON Investigators, The OCAC Consortium & the Cimba Consortium, Mar 2022, In: European Journal of Human Genetics. 30, 3, p. 349-362 14 p.

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Open Access

31 Scopus citations

Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants

ENIGMA Consortium & CIMBA Consortium, Jan 2022, In: Genetics in Medicine. 24, 1, p. 119-129 11 p.

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Open Access

16 Scopus citations

2021

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators & ABCTB Investigators, Dec 1 2021, In: Nature Communications. 12, 1, 1078.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Albert de la Chapelle (1933-2020)

Toland, A. E. & Hampel, H., Feb 4 2021, In: American Journal of Human Genetics. 108, 2, p. 214-216 3 p.

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Open Access

Association between Smoking and Molecular Subtypes of Colorectal Cancer

Wang, X., Amitay, E., Harrison, T. A., Banbury, B. L., Berndt, S. I., Brenner, H., Buchanan, D. D., Campbell, P. T., Cao, Y., Chan, A. T., Chang-Claude, J., Gallinger, S. J., Giannakis, M., Giles, G. G., Gunter, M. J., Hopper, J. L., Jenkins, M. A., Lin, Y., Moreno, V. & Nishihara, R. & 14 others, Newcomb, P. A., Ogino, S., Phipps, A. I., Sakoda, L. C., Schoen, R. E., Slattery, M. L., Song, M., Sun, W., Thibodeau, S. N., Toland, A. E., Van Guelpen, B., Woods, M. O., Hsu, L. & Peters, U., Aug 1 2021, In: JNCI Cancer Spectrum. 5, 4, pkab056.

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Open Access

12 Scopus citations

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

NBCS Collaborators, kConFab Investigators & ABCTB Investigators, Jul 2021, In: American Journal of Human Genetics. 108, 7, p. 1190-1203 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Genetic architectures of proximal and distal colorectal cancer are partly distinct

Huyghe, J. R., Harrison, T. A., Bien, S. A., Hampel, H., Figueiredo, J. C., Schmit, S. L., Conti, D. V., Chen, S., Qu, C., Lin, Y., Barfield, R., Baron, J. A., Cross, A. J., Diergaarde, B., Duggan, D., Harlid, S., Imaz, L., Kang, H. M., Levine, D. M. & Perduca, V. & 121 others, Perez-Cornago, A., Sakoda, L. C., Schumacher, F. R., Slattery, M. L., Toland, A. E., Van Duijnhoven, F. J. B., Van Guelpen, B., Agudo, A., Albanes, D., Alonso, M. H., Anderson, K., Arnau-Collell, C., Arndt, V., Banbury, B. L., Bassik, M. C., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Boutron-Ruault, M. C., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Caan, B. J., Campbell, P. T., Carr, P. R., Castells, A., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Curtis, K. R., De La Chapelle, A., Easton, D. F., English, D. R., Feskens, E. J. M., Gala, M., Gallinger, S. J., Gauderman, W. J., Giles, G. G., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hoffmeister, M., Hopper, J. L., Hsu, W. L., Huang, W. Y., Hudson, T. J., Jenab, M., Jenkins, M. A., Joshi, A. D., Keku, T. O., Kooperberg, C., Kühn, T., Küry, S., Le Marchand, L., Lejbkowicz, F., Li, C. I., Li, L., Lieb, W., Lindblom, A., Lindor, N. M., Männistö, S., Markowitz, S. D., Milne, R. L., Moreno, L., Murphy, N., Nassir, R., Offit, K., Ogino, S., Panico, S., Parfrey, P. S., Pearlman, R., Pharoah, P. D. P., Phipps, A. I., Platz, E. A., Potter, J. D., Prentice, R. L., Qi, L., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Schafmayer, C., Schoen, R. E., Seminara, D., Song, M., Su, Y. R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Trichopoulou, A., Ulrich, C. M., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Wolk, A., Woods, M. O., Wu, A. H., Abecasis, G. R., Nickerson, D. A., Scacheri, P. C., Kundaje, A., Casey, G., Gruber, S. B., Hsu, L., Moreno, V., Hayes, R. B., Newcomb, P. A. & Peters, U., Jul 1 2021, In: Gut. 70, 7, p. 1325-1334 10 p.

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47 Scopus citations

Impact of Previous Genetic Counseling and Objective Numeracy on Accurate Interpretation of a Pharmacogenetics Test Report

Drelles, K., Pilarski, R., Manickam, K., Shoben, A. B. & Toland, A. E., Feb 2021, In: Public Health Genomics. 24, 1-2, p. 26-32 7 p.

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Open Access

9 Scopus citations

Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies

Hidaka, A., Harrison, T. A., Cao, Y., Sakoda, L. C., Barfield, R., Giannakis, M., Song, M., Phipps, A. I., Figueiredo, J. C., Zaidi, S. H., Toland, A. E., Amitay, E. L., Berndt, S. I., Borozan, I., Chan, A. T., Gallinger, S., Gunter, M. J., Guinter, M. A., Harlid, S. & Hampel, H. & 22 others, Jenkins, M. A., Lin, Y., Moreno, V., Newcomb, P. A., Nishihara, R., Ogino, S., Obon-Santacana, M., Parfrey, P. S., Potter, J. D., Slattery, M. L., Steinfelder, R. S., Um, C. Y., Wang, X., Woods, M. O., van Guelpen, B., Thibodeau, S. N., Hoffmeister, M., Sun, W., Hsu, L., Buchanan, D. D., Campbell, P. T. & Peters, U., Oct 15 2021, In: Cancer Research. 80, 20, p. 4578-4590 13 p.

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30 Scopus citations

Machine learning approaches reveal subtle differences in breathing and sleep fragmentation in Phox2b-derived astrocytes ablated mice

Silva, T. M., Borniger, J. C., Alves, M. J., Correa, D. A., Zhao, J., Fadda, P., Toland, A. E., Takakura, A. C., Moreira, T. S., Czeisler, C. M. & Otero, J. J., Apr 2021, In: Journal of neurophysiology. 125, 4, p. 1164-1179 16 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Oncogenetic network estimation with disjunctive Bayesian networks

Nicol, P. B., Coombes, K., Deaver, C., Chkrebtii, O., Paul, S., Toland, A. E. & Asiaee, A., Jun 2021, In: Computational and Systems Oncology. 1, 2, e1027.

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Open Access

4 Scopus citations

The p.Ser64Leu and p.Pro104Leu missense variants of PALB2 identified in familial pancreatic cancer patients compromise the DNA damage response

Zhang, Y., Park, J. Y., Zhang, F., Olson, S. H., Orlow, I., Li, Y., Kurtz, R. C., Ladanyi, M., Chen, J., Toland, A. E., Zhang, L. & Andreassen, P. R., Feb 2021, In: Human Mutation. 42, 2, p. 150-163 14 p.

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The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

GEMO Study Collaborators, EMBRACE Collaborators, OCGN Investigators, HEBON Investigators & kConFab Investigators, Sep 2021, In: Genetics in Medicine. 23, 9, p. 1726-1737 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2020

Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness

Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittom, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J. & Balmaña, J. & 239 others, Barkardottir, R. B., Barnes, D. R., Barroso, A., Barrowdale, D., Belotti, M., Benitez, J., Bertelsen, B., Blok, M. J., Bodrogi, I., Bonadona, V., Bonanni, B., Bondavalli, D., Boonen, S. E., Borde, J., Borg, A., Bradbury, A. R., Brady, A., Brewer, C., Brunet, J., Buecher, B., Buys, S. S., Cabezas-Camarero, S., Caldes, T., Caliebe, A., Caligo, M. A., Calvello, M., Campbell, I. G., Carnevali, I., Carrasco, E., Chan, T. L., Chu, A. T. W., Chung, W. K., Claes, K. B. M., Cook, J., Cortesi, L., Couch, F. J., Daly, M. B., Damante, G., Darder, E., Davidson, R., De La Hoya, M., Della Puppa, L., Dennis, J., Díez, O., Ding, Y. C., Ditsch, N., Domchek, S. M., Donaldson, A., Dworniczak, B., Easton, D. F., Eccles, D. M., Eeles, R. A., Ehrencrona, H., Ejlertsen, B., Engel, C., Evans, D. G., Faivre, L., Faust, U., Feliubadalo, L., Foretova, L., Fostira, F., Fountzilas, G., Frost, D., García-Barberan, V., Garre, P., Gauthier-Villars, M., Geczi, L., Gehrig, A., Gerdes, A. M., Gesta, P., Giannini, G., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gutierrez-Barrera, A. M., Hahnen, E., Hamann, U., Hauke, J., Herold, N., Hogervorst, F. B. L., Honisch, E., Hopper, J. L., Hulick, P. J., Izatt, L., Jager, A., James, P., Janavicius, R., Jensen, U. B., Jensen, T. D., Johannsson, O. T., John, E. M., Joseph, V., Kang, E., Kast, K., Kiiski, J. I., Kim, S. W., Kim, Z., Ko, K. P., Konstantopoulou, I., Kramer, G., Krogh, L., Kruse, T. A., Kwong, A., Larsen, M., Lasset, C., Lautrup, C., Lazaro, C., Lee, J., Lee, J. W., Lee, M. H., Lemke, J., Lesueur, F., Liljegren, A., Lindblom, A., Llovet, P., Lopez-Fernandez, A., Lopez-Perolio, I., Lorca, V., Loud, J. T., Ma, E. S. K., Mai, P. L., Manoukian, S., Mari, V., Martin, L., Matricardi, L., Mebirouk, N., Medici, V., Meijers-Heijboer, H. E. J., Meindl, A., Mensenkamp, A. R., Miller, C., Gomes, D. M., Montagna, M., Mooij, T. M., Moserle, L., Mouret-Fourme, E., Mulligan, A. M., Nathanson, K. L., Navratilova, M., Nevanlinna, H., Niederacher, D., Cilius Nielsen, F. C., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O. I., Ong, K. R., Osorio, A., Ott, C. E., Palli, D., Park, S. K., Parsons, M. T., Pedersen, I. S., Peissel, B., Peixoto, A., Perez-Segura, P., Peterlongo, P., Petersen, A. H., Porteous, M. E., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Rashid, M. U., Rhiem, K., Rizzolo, P., Robson, M. E., Rookus, M. A., Rossing, C. M., Ruddy, K. J., Santos, C., Saule, C., Scarpitta, R., Schmutzler, R. K., Schuster, H., Senter, L., Seynaeve, C. M., Shah, P. D., Sharma, P., Shin, V. Y., Silvestri, V., Simard, J., Singer, C. F., Skytte, A. B., Snape, K., Solano, A. R., Soucy, P., Southey, M. C., Spurdle, A. B., Steele, L., Steinemann, D., Stoppa-Lyonnet, D., Stradella, A., Sunde, L., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teo, S. H., Thomassen, M., Tibiletti, M. G., Tischkowitz, M., Tognazzo, S., Toland, A. E., Tommasi, S., Torres, D., Toss, A., Trainer, A. H., Tung, N., Van Asperen, C. J., Van Der Baan, F. H., Van Der Kolk, L. E., Van Der Luijt, R. B., Van Hest, L. P., Varesco, L., Varon-Mateeva, R., Viel, A., Vierstrate, J., Villa, R., Von Wachenfeldt, A., Wagner, P., Wang-Gohrke, S., Wappenschmidt, B., Weitzel, J. N., Wieme, G., Yadav, S., Yannoukakos, D., Yoon, S. Y., Zanzottera, C., Zorn, K. K., D’Amico, A. V., Freedman, M. L., Pomerantz, M. M., Chenevix-Trench, G., Antoniou, A. C., Neuhausen, S. L., Ottini, L., Nielsen, H. R. & Rebbeck, T. R., Feb 1 2020, In: Cancer Research. 80, 3, p. 624-638 15 p.

Research output: Contribution to journal › Article › peer-review

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38 Scopus citations

Characterization of the Cancer Spectrum in Men with Germline BRCA1 and BRCA2 Pathogenic Variants: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Silvestri, V., Leslie, G., Barnes, D. R., Agnarsson, B. A., Aittomäki, K., Alducci, E., Andrulis, I. L., Barkardottir, R. B., Barroso, A., Barrowdale, D., Benitez, J., Bonanni, B., Borg, A., Buys, S. S., Caldés, T., Caligo, M. A., Capalbo, C., Campbell, I., Chung, W. K. & Claes, K. B. M. & 103 others, Colonna, S. V., Cortesi, L., Couch, F. J., De La Hoya, M., Diez, O., Ding, Y. C., Domchek, S., Easton, D. F., Ejlertsen, B., Engel, C., Evans, D. G., Feliubadalò, L., Foretova, L., Fostira, F., Géczi, L., Gerdes, A. M., Glendon, G., Godwin, A. K., Goldgar, D. E., Hahnen, E., Hogervorst, F. B. L., Hopper, J. L., Hulick, P. J., Isaacs, C., Izquierdo, A., James, P. A., Janavicius, R., Jensen, U. B., John, E. M., Joseph, V., Konstantopoulou, I., Kurian, A. W., Kwong, A., Landucci, E., Lesueur, F., Loud, J. T., Machackova, E., Mai, P. L., Majidzadeh-A, K., Manoukian, S., Montagna, M., Moserle, L., Mulligan, A. M., Nathanson, K. L., Nevanlinna, H., Ngeow Yuen Ye, J., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O. I., Osorio, A., Papi, L., Park, S. K., Pedersen, I. S., Perez-Segura, P., Petersen, A. H., Pinto, P., Porfirio, B., Pujana, M. A., Radice, P., Rantala, J., Rashid, M. U., Rosenzweig, B., Rossing, M., Santamariña, M., Schmutzler, R. K., Senter, L., Simard, J., Singer, C. F., Solano, A. R., Southey, M. C., Steele, L., Steinsnyder, Z., Stoppa-Lyonnet, D., Tan, Y. Y., Teixeira, M. R., Teo, S. H., Terry, M. B., Thomassen, M., Toland, A. E., Torres-Esquius, S., Tung, N., Van Asperen, C. J., Vega, A., Viel, A., Vierstraete, J., Wappenschmidt, B., Weitzel, J. N., Wieme, G., Yoon, S. Y., Zorn, K. K., Mcguffog, L., Parsons, M. T., Hamann, U., Greene, M. H., Kirk, J. A., Neuhausen, S. L., Rebbeck, T. R., Tischkowitz, M., Chenevix-Trench, G., Antoniou, A. C., Friedman, E. & Ottini, L., Aug 2020, In: JAMA Oncology. 6, 8, p. 1218-1230 13 p.

Research output: Contribution to journal › Article › peer-review

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46 Scopus citations

Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Archambault, A. N., Su, Y. R., Jeon, J., Thomas, M., Lin, Y., Conti, D. V., Win, A. K., Sakoda, L. C., Lansdorp-Vogelaar, I., Peterse, E. F. P., Zauber, A. G., Duggan, D., Holowatyj, A. N., Huyghe, J. R., Brenner, H., Cotterchio, M., Bézieau, S., Schmit, S. L., Edlund, C. K. & Southey, M. C. & 114 others, MacInnis, R. J., Campbell, P. T., Chang-Claude, J., Slattery, M. L., Chan, A. T., Joshi, A. D., Song, M., Cao, Y., Woods, M. O., White, E., Weinstein, S. J., Ulrich, C. M., Hoffmeister, M., Bien, S. A., Harrison, T. A., Hampe, J., Li, C. I., Schafmayer, C., Offit, K., Pharoah, P. D., Moreno, V., Lindblom, A., Wolk, A., Wu, A. H., Li, L., Gunter, M. J., Gsur, A., Keku, T. O., Pearlman, R., Bishop, D. T., Castellví-Bel, S., Moreira, L., Vodicka, P., Kampman, E., Giles, G. G., Albanes, D., Baron, J. A., Berndt, S. I., Brezina, S., Buch, S., Buchanan, D. D., Trichopoulou, A., Severi, G., Chirlaque, M. D., Sánchez, M. J., Palli, D., Kühn, T., Murphy, N., Cross, A. J., Burnett-Hartman, A. N., Chanock, S. J., de la Chapelle, A., Easton, D. F., Elliott, F., English, D. R., Feskens, E. J. M., FitzGerald, L. M., Goodman, P. J., Hopper, J. L., Hudson, T. J., Hunter, D. J., Jacobs, E. J., Joshu, C. E., Küry, S., Markowitz, S. D., Milne, R. L., Platz, E. A., Rennert, G., Rennert, H. S., Schumacher, F. R., Sandler, R. S., Seminara, D., Tangen, C. M., Thibodeau, S. N., Toland, A. E., van Duijnhoven, F. J. B., Visvanathan, K., Vodickova, L., Potter, J. D., Männistö, S., Weigl, K., Figueiredo, J., Martín, V., Larsson, S. C., Parfrey, P. S., Huang, W. Y., Lenz, H. J., Castelao, J. E., Gago-Dominguez, M., Muñoz-Garzón, V., Mancao, C., Haiman, C. A., Wilkens, L. R., Siegel, E., Barry, E., Younghusband, B., Van Guelpen, B., Harlid, S., Zeleniuch-Jacquotte, A., Liang, P. S., Du, M., Casey, G., Lindor, N. M., Le Marchand, L., Gallinger, S. J., Jenkins, M. A., Newcomb, P. A., Gruber, S. B., Schoen, R. E., Hampel, H., Corley, D. A., Hsu, L., Peters, U. & Hayes, R. B., Apr 2020, In: Gastroenterology. 158, 5, p. 1274-1286.e12

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Open Access

123 Scopus citations

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators & ABCTB Investigators, Jan 1 2020, In: Nature Genetics. 52, 1, p. 56-73 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

116 Scopus citations

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

kConFab Investigators, ABCTB Investigators, EMBRACE Study & GEMO Study Collaborators, Jun 1 2020, In: Nature Genetics. 52, 6, p. 572-581 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

266 Scopus citations

Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma

Sarin, K. Y., Lin, Y., Daneshjou, R., Ziyatdinov, A., Thorleifsson, G., Rubin, A., Pardo, L. M., Wu, W., Khavari, P. A., Uitterlinden, A., Nijsten, T., Toland, A. E., Olafsson, J. H., Sigurgeirsson, B., Thorisdottir, K., Jorgensen, E., Whittemore, A. S., Kraft, P., Stacey, S. N. & Stefansson, K. & 2 others, Asgari, M. M. & Han, J., Dec 1 2020, In: Nature Communications. 11, 1, 820.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019

Giri, V. N., Knudsen, K. E., Kelly, W. K., Cheng, H. H., Cooney, K. A., Cookson, M. S., Dahut, W., Weissman, S., Soule, H. R., Petrylak, D. P., Dicker, A. P., AlDubayan, S. H., Toland, A. E., Pritchard, C. C., Pettaway, C. A., Daly, M. B., Mohler, J. L., Parsons, J. K., Carroll, P. R. & Pilarski, R. & 72 others, Blanco, A., Woodson, A., Rahm, A., Taplin, M. E., Polascik, T. J., Helfand, B. T., Hyatt, C., Morgans, A. K., Feng, F., Mullane, M., Powers, J., Concepcion, R., Lin, D. W., Wender, R., Mark, J. R., Costello, A., Burnett, A. L., Sartor, O., Isaacs, W. B., Xu, J., Weitzel, J., Andriole, G. L., Beltran, H., Briganti, A., Byrne, L., Calvaresi, A., Chandrasekar, T., Chen, D. Y. T., Den, R. B., Dobi, A., Crawford, E. D., Eastham, J., Eggener, S., Freedman, M. L., Garnick, M., Gomella, P. T., Handley, N., Hurwitz, M. D., Izes, J., Karnes, R. J., Lallas, C., Languino, L., Loeb, S., Lopez, A. M., Loughlin, K. R., Lu-Yao, G., Malkowicz, S. B., Mann, M., Mille, P., Miner, M. M., Morgan, T., Moreno, J., Mucci, L., Myers, R. E., Nielsen, S. M., O’Neil, B., Pinover, W., Pinto, P., Poage, W., Raj, G. V., Rebbeck, T. R., Ryan, C., Sandler, H., Schiewer, M., D. Scott, E. M., Szymaniak, B., Tester, W., Trabulsi, E. J., Vapiwala, N., Yu, E. Y., Zeigler-Johnson, C. & Gomella, L. G., Aug 20 2020, In: Journal of Clinical Oncology. 38, 24, p. 2798-2811 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

185 Scopus citations

Maternal age at delivery and fertility of the next generation

Reynolds, T. S., Lynch, C. D., Hade, E. M., Allain, D. C., Westman, J. A. & Toland, A. E., Nov 1 2020, In: Paediatric and Perinatal Epidemiology. 34, 6, p. 629-636 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Metastatic breast cancer patient perceptions of somatic tumor genomic testing

Adams, E. J., Asad, S., Reinbolt, R., Collier, K. A., Abdel-Rasoul, M., Gillespie, S., Chen, J. L., Cherian, M. A., Noonan, A. M., Sardesai, S., Vandeusen, J., Wesolowski, R., Williams, N., Shapiro, C. L., Macrae, E. R., Pilarski, R., Toland, A. E., Senter, L., Ramaswamy, B. & Lee, C. N. & 2 others, Lustberg, M. B. & Stover, D. G., May 6 2020, In: BMC Cancer. 20, 1, 389.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Amanda E. Toland

Research output

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