Projects per year
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Dive into the research topics where Deliang Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Delineating how retinoic acids regulate lipid metabolism in glioblastoma and their resistance mechanisms
Guo, D. (PI)
07/1/20 → 06/30/25
Project: Research
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Defining the molecular mechanisms regulating the hexosamine-N-glycosylation pathway in glioblastoma
Guo, D. (PI) & Chakravarti, A. (CoPI)
07/1/19 → 06/30/24
Project: Research
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Determining the role of lipid droplets and their therapeutic potential in glioblastoma
Guo, D. (PI)
National Institute of Neurological Disorders and Stroke
09/15/18 → 06/30/24
Project: Research
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Targeting the cholesterol metabolism to treat glioblastoma
Guo, D. (PI)
National Institute of Neurological Disorders and Stroke
08/1/13 → 07/31/19
Project: Research
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Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
Zhong, Y., Geng, F., Mazik, L., Yin, X., Becker, A. P., Mohammed, S., Su, H., Xing, E., Kou, Y., Chiang, C. Y., Fan, Y., Guo, Y., Wang, Q., Li, P. K., Mo, X., Lefai, E., He, L., Cheng, X., Zhang, X. & Chakravarti, A. & 1 others, , Sep 17 2024, In: Cell Reports Medicine. 5, 9, 101706.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
SREBF1/SREBP-1 concurrently regulates lipid synthesis and lipophagy to maintain lipid homeostasis and tumor growth
Geng, F. & Guo, D., 2024, In: Autophagy. 20, 5, p. 1183-1185 3 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
STAT3 activation of SCAP-SREBP-1 signaling upregulates fatty acid synthesis to promote tumor growth
Fan, Y., Zhang, R., Wang, C., Pan, M., Geng, F., Zhong, Y., Su, H., Kou, Y., Mo, X., Lefai, E., Han, X., Chakravarti, A. & Guo, D., Jun 2024, In: Journal of Biological Chemistry. 300, 6, 107351.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity
Prasad, C. B., Oo, A., Liu, Y., Qiu, Z., Zhong, Y., Li, N., Singh, D., Xin, X., Cho, Y. J., Li, Z., Zhang, X., Yan, C., Zheng, Q., Wang, Q. E., Guo, D., Kim, B. & Zhang, J., Dec 2024, In: Nature Communications. 15, 1, 4667.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Tumor cells utilize acetate for tumor growth and immune evasion
Sun, P., Liu, J. & Guo, D., Sep 2024, In: MedComm. 5, 9, e717.Research output: Contribution to journal › Article › peer-review
Open Access