Projects per year
Fingerprint
Dive into the research topics where Jack Charles Yalowich is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 5 Finished
-
Novel Topoisomerase II alpha isoform as a drug resistance determinant
Yalowich, J. C. (PI) & Elton, T. S. (CoPI)
12/1/18 → 11/30/23
Project: Research
-
Mechanisms and Prevention of Etoposide-Induced Leukemia
Yalowich, J. C. (PI)
07/1/01 → 05/31/14
Project: Research
-
MECHANISMS OF ACTION AND RESISTANCE TO ICRF187
Yalowich, J. C. (PI)
07/1/98 → 06/30/03
Project: Research
-
VP-16/BRYOSTATIN 1 FOR TREATMENT OF RESISTANT LEUKEMIA
Yalowich, J. C. (PI)
09/1/97 → 08/31/00
Project: Research
-
MECHANISMS AND MODULATION OF ETOPOSIDE--VP-16 RESISTANCE
Yalowich, J. C. (PI)
07/1/89 → 06/30/93
Project: Research
-
Circumvention of Topoisomerase IIa Intron 19 Intronic Polyadenylation in Acquired Etoposide-Resistant Human Leukemia K562 Cells
Wang, X., Carvajal-Moreno, J., Zhao, X., Li, J., Hernandez, V. A., Yalowich, J. C. & Elton, T. S., Jul 1 2024, In: Molecular pharmacology. 106, 1, p. 33-46 14 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Development of Novel Bacterial Topoisomerase Inhibitors Assisted by Computational Screening
Powell, J. W., Mann, C. A., Toth, P. D., Nolan, S., Steinert, A., Ove, C., Seffernick, J. T., Wozniak, D. J., Kebriaei, R., Lindert, S., Osheroff, N., Yalowich, J. C. & Mitton-Fry, M. J., Aug 8 2024, In: ACS Medicinal Chemistry Letters. 15, 8, p. 1287-1297 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Use of CRISPR/Cas9 with Homology-Directed Repair to Gene-Edit Topoisomerase IIb in Human Leukemia K562 Cells: Generation of a Resistance Phenotype
Carvajal-Moreno, J., Wang, X., Hernandez, V. A., Mondal, M., Zhao, X., Yalowich, J. C. & Elton, T. S., May 1 2024, In: Journal of Pharmacology and Experimental Therapeutics. 389, 2, p. 186-196 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Actions of a Novel Bacterial Topoisomerase Inhibitor against Neisseria gonorrhoeae Gyrase and Topoisomerase IV: Enhancement of Double-Stranded DNA Breaks
Dauda, S. E., Collins, J. A., Byl, J. A. W., Lu, Y., Yalowich, J. C., Mitton-Fry, M. J. & Osheroff, N., Aug 2023, In: International journal of molecular sciences. 24, 15, 12107.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Effects of hsa-miR-9-3p and hsa-miR-9-5p on Topoisomerase IIb Expression in Human Leukemia K562 Cells with Acquired Resistance to Etoposide
Carvajal-Moreno, J., Hernandez, V. A., Wang, X., Li, J., Yalowich, J. C. & Elton, T. S., Feb 1 2023, In: Journal of Pharmacology and Experimental Therapeutics. 384, 2, p. 265-276 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations