Projects per year
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Dive into the research topics where Michael Root is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Translational Research in Cancer
Chapman, A. (PI), Alder, H. (CoPI), Lopez, A. M. (CoPI), Aplin, A. E. (CoPI), Baserga, R. (CoPI), Bast, R. (CoPI), Benovic, J. L. (CoPI), Berger, A. C. (CoPI), Boman, B. (CoPI), Jameson, B. A. (CoPI), Brenner, C. M. (CoPI), Buchberg, A. M. (CoPI), Wigdahl, B. B. (CoPI), Carabasi, M. (CoPI), Catalano, R. (CoPI), Cingolani, G. (CoPI), Croce, C. M. (CoPI), Giraudo, C. C. G. (CoPI), Davidson, R. L. (CoPI), Dicker, A. (CoPI), Dubois, G. C. (CoPI), Ehrlich, G. D. (CoPI), Eischen, C. M. (CoPI), Fishel, R. A. (CoPI), Flomenberg, N. (CoPI), Fortina, P. M. (CoPI), Kim, F. F. J. (CoPI), Germann, M. W. (CoPI), Hauck, W. W. (CoPI), Huesser, M. H. (CoPI), Hyslop, T. M. (CoPI), Jiang, W. (CoPI), London, J. W. (CoPI), Kasner, M. (CoPI), Keen, J. H. (CoPI), Kelly, W. K. (CoPI), Knudsen, K. E. (CoPI), Korngold, R. (CoPI), Siracusa, L. L. D. (CoPI), Landel, C. P. (CoPI), Leader, A. (CoPI), Leiby, B. (CoPI), Lisanti, M. P. (CoPI), Harshyne, L. (CoPI), Manser, T. (CoPI), Reginato, M. M. J. (CoPI), McCue, P. A. (CoPI), Mckenzie, S. (CoPI), Mervis, S. (CoPI), Schnell, M. M. J. (CoPI), Simone, N. L. (CoPI), Oneill, S. (CoPI), Pascal, J. (CoPI), Peiper, S. (CoPI), Perussia, B. (CoPI), Pestell, R. G. (CoPI), Pestell, R. G. (CoPI), Jepsen, P. P. L. (CoPI), Root, M. (CoPI), Rui, H. (CoPI), Sigal, L. J. (CoPI), Silver, D. P. (CoPI), Siracusa, L. D. (CoPI), Thakur, M. L. (CoPI), Waldman, S. A. (CoPI), Wedegaertner, P. B. (CoPI), Witkiewicz, A. (CoPI), Jiang, W. W. (CoPI), Yunis, J. J. (CoPI), Zhang, J. (CoPI), Baserga, R. L. (CoPI), Jepsen, P. L. (CoPI), London, J. W. (CoPI) & Siracusa, N. L. D. (CoPI)
06/22/95 → 05/31/25
Project: Research
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Mechanisms of HIV-1 Env-Mediated Membrane Fusion
Root, M. (CoPI)
National Institute of Allergy and Infectious Diseases
05/1/20 → 04/30/21
Project: Research
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X-Ray Crystallography and Macromolecular Characterization
Root, M. (PI), Root, M. M. J. (PI) & Cingolani, G. (PI)
04/1/18 → 05/31/23
Project: Research
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Structure of SARS Coronavirus Spike Glycoprotein
Root, M. (PI)
National Institute of Allergy and Infectious Diseases
09/30/04 → 08/31/07
Project: Research
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Mechanisms of HIV-1 Env-Mediated Membrane Fusion
Root, M. (PI)
National Institute of General Medical Sciences
09/1/02 → 04/30/20
Project: Research
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Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env
Schapiro, H. M., Khasnis, M. D., Ahn, K., Karagiaridi, A., Hayden, S., Cilento, M. E. & Root, M. J., May 2022, In: PLoS pathogens. 18, 5, e101053.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators
Zhang, S., Holmes, A. P., Dick, A., Rashad, A. A., Enríquez Rodríguez, L., Canziani, G. A., Root, M. J. & Chaiken, I. M., Dec 2021, In: Retrovirology. 18, 1, 31.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Characterization of resistance to a potent d-peptide HIV entry inhibitor
Smith, A. R., Weinstock, M. T., Siglin, A. E., Whitby, F. G., Francis, J. N., Hill, C. P., Eckert, D. M., Root, M. J. & Kay, M. S., Oct 22 2019, In: Retrovirology. 16, 1, 28.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Complex interplay of kinetic factors governs the synergistic properties of HIV-1 entry inhibitors
Ahn, K. W. & Root, M. J., Oct 6 2017, In: Journal of Biological Chemistry. 292, 40, p. 16498-16510 13 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Site-Specific Polymer Attachment to HR2 Peptide Fusion Inhibitors against HIV-1 Decreases Binding Association Rates and Dissociation Rates Rather Than Binding Affinity
Danial, M., Stauffer, A. N., Wurm, F. R., Root, M. J. & Klok, H. A., Mar 15 2017, In: Bioconjugate Chemistry. 28, 3, p. 701-712 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations