Projects per year
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Collaborations and top research areas from the last five years
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Mechanistic characterization of JNK2α variants in alcohol-caused heart failure
Ai, X. (PI)
National Institute on Alcohol Abuse and Alcoholism
09/20/25 → 06/30/27
Project: Research
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The Stress Response Kinase JNK and Alcohol Evoked Atrial Fibrillation
Ai, X. (PI), Chen, S. R. W. (CoPI) & Fill, M. (CoPI)
National Institute on Alcohol Abuse and Alcoholism
04/15/17 → 03/31/22
Project: Research
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Core B: Human Cell and Tissue Core
Ai, X. (PI)
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
06/1/16 → 05/31/21
Project: Research
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JNK Suppression of Connexin43 Enhances Atrial Fibrillation in Aged Atria
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
07/3/12 → 07/31/18
Project: Research
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JNK2 Is a Stress Integrator Driving Atrial Fibrillation Pathogenesis in Aging via Gut-Heart Crosstalk
Yan, J., Carrillo, E., Kohli, A., Khanal, S., Ricchiuti, N., DeSantiago, J., Wan, X., Han, M., Richardson, A., Yang, M., Rondon, J., Shen, L., Sun, J., Liang, Q., Hund, T. J., Meller, J., Deschenes, I., Bare, D. J. & Ai, X., Jun 23 2026, In: Circulation. 153, 25, p. 2029-2043 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
TRPM7 Deficiency Protects Against Myocardial Ischemia-Reperfusion Injury by Regulating Intracellular Zn2+ Homeostasis
Li, X., Li, X., Li, C. X., Feng, J., Yue, Z., Yan, J., Matsushita, M., Qyang, Y., Runnels, L. W., Ai, X. & Yue, L., Feb 6 2026, In: Circulation. Publish Ahead of PrintResearch output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Stress-Induced calcium mishandling in cardiac (Patho)physiology
Bare, D. J. & Ai, X., Dec 2025, In: Cellular and Molecular Life Sciences. 82, 1, 437.Research output: Contribution to journal › Review article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
The two-pore K+ channel TREK-1 regulates pressure overload-induced cardiac remodeling
Johnson, C. M. L., Nassal, D. M., Winkle, A. J., Buck, B., Xu, X., Wan, X., Han, M., Lococo, S., Leahy, N., Mohta, S., Shaheen, R., Cavus, O., Kohli, A., Cao, Y., Refaey, M. E., Smith, S., Ai, X., Deschênes, I. & Hund, T. J., Jul 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 329, 1, p. H178-H190Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Alda-1 attenuation of binge alcohol-caused atrial arrhythmias through a novel mechanism of suppressed c-Jun N-terminal Kinase-2 activity
Yan, J., Khanal, S., Cao, Y., Ricchiuti, N., Nani, A., Chen, S. R. W., Fill, M., Bare, D. J. & Ai, X., Dec 2024, In: Journal of Molecular and Cellular Cardiology. 197, p. 11-19 9 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations