@inbook{0ccc9f2af6194435b21d0e5f959c9e3c,
title = "A murine model of myocardial ischemia–Reperfusion Injury",
abstract = "Ligation of the left anterior descending (LAD) coronary artery in the mouse heart is a widely used model to simulate myocardial infarction and ischemia–reperfusion injury. Here we describe a ligation technique routinely performed in our laboratory to induce myocardial infarction that may be used to study ischemia–reperfusion injury in the myocardium. The methods described enhance location of the LAD coronary artery to allow for accurate ligation, thus increasing reproducibility of infarct size and location.",
keywords = "LAD ligation, Left anterior descending coronary artery, Myocardial infarction, Myocardial ischemia–reperfusion, Permanent ligation",
author = "Zhaobin Xu and McElhanon, \{Kevin E.\} and Beck, \{Eric X.\} and Weisleder, \{Noah L.\}",
year = "2018",
month = jan,
day = "1",
doi = "10.1007/978-1-4939-7526-6\_12",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "145--153",
booktitle = "Methods in Molecular Biology",
}