Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations

Benedito A. Carneiro; Katharine Ann Collier; Rebecca J. Nagy; Sahithi Pamarthy; Vinay Sagar; Stephen Fairclough; Justin Odegaard; Richard B. Lanman; Ricardo Costa; Timothy Taxter; Timothy M. Kuzel; Alice Fan; Young Kwang Chae; Massimo Cristofanilli; Maha H. Hussain; Sarki A. Abdulkadir; Francis J. Giles

doi:10.1200/PO.17.00176

Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations

Benedito A. Carneiro
, Katharine Ann Collier
, Rebecca J. Nagy
, Sahithi Pamarthy
, Vinay Sagar
, Stephen Fairclough
, Justin Odegaard
, Richard B. Lanman
, Ricardo Costa
, Timothy Taxter
, Timothy M. Kuzel
, Alice Fan
, Young Kwang Chae
, Massimo Cristofanilli
, Maha H. Hussain
, Sarki A. Abdulkadir
, Francis J. Giles

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1-8
Number of pages	8
Journal	JCO Precision Oncology
Volume	2
DOIs	https://doi.org/10.1200/PO.17.00176
State	Published - Feb 14 2018

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10.1200/PO.17.00176

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Carneiro, B. A., Collier, K. A., Nagy, R. J., Pamarthy, S., Sagar, V., Fairclough, S., Odegaard, J., Lanman, R. B., Costa, R., Taxter, T., Kuzel, T. M., Fan, A., Chae, Y. K., Cristofanilli, M., Hussain, M. H., Abdulkadir, S. A., & Giles, F. J. (2018). Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations. JCO Precision Oncology, 2, 1-8. https://doi.org/10.1200/PO.17.00176

@article{b1a7168319f5442f8c717040817776de,

title = "Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations",

author = "Carneiro, \{Benedito A.\} and Collier, \{Katharine Ann\} and Nagy, \{Rebecca J.\} and Sahithi Pamarthy and Vinay Sagar and Stephen Fairclough and Justin Odegaard and Lanman, \{Richard B.\} and Ricardo Costa and Timothy Taxter and Kuzel, \{Timothy M.\} and Alice Fan and Chae, \{Young Kwang\} and Massimo Cristofanilli and Hussain, \{Maha H.\} and Abdulkadir, \{Sarki A.\} and Giles, \{Francis J.\}",

year = "2018",

month = feb,

day = "14",

doi = "10.1200/PO.17.00176",

language = "English",

volume = "2",

pages = "1--8",

journal = "JCO Precision Oncology",

issn = "2473-4284",

}

Carneiro, BA, Collier, KA, Nagy, RJ, Pamarthy, S, Sagar, V, Fairclough, S, Odegaard, J, Lanman, RB, Costa, R, Taxter, T, Kuzel, TM, Fan, A, Chae, YK, Cristofanilli, M, Hussain, MH, Abdulkadir, SA & Giles, FJ 2018, 'Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations', JCO Precision Oncology, vol. 2, pp. 1-8. https://doi.org/10.1200/PO.17.00176

Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations. / Carneiro, Benedito A.; Collier, Katharine Ann; Nagy, Rebecca J. et al.
In: JCO Precision Oncology, Vol. 2, 14.02.2018, p. 1-8.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations

AU - Carneiro, Benedito A.

AU - Collier, Katharine Ann

AU - Nagy, Rebecca J.

AU - Pamarthy, Sahithi

AU - Sagar, Vinay

AU - Fairclough, Stephen

AU - Odegaard, Justin

AU - Lanman, Richard B.

AU - Costa, Ricardo

AU - Taxter, Timothy

AU - Kuzel, Timothy M.

AU - Fan, Alice

AU - Chae, Young Kwang

AU - Cristofanilli, Massimo

AU - Hussain, Maha H.

AU - Abdulkadir, Sarki A.

AU - Giles, Francis J.

PY - 2018/2/14

Y1 - 2018/2/14

UR - https://www.scopus.com/pages/publications/85055689876

U2 - 10.1200/PO.17.00176

DO - 10.1200/PO.17.00176

M3 - Article

AN - SCOPUS:85055689876

SN - 2473-4284

VL - 2

SP - 1

EP - 8

JO - JCO Precision Oncology

JF - JCO Precision Oncology

ER -

Acquired resistance to poly (ADP-ribose) polymerase inhibitor olaparib in BRCA2-associated prostate cancer resulting from biallelic BRCA2 reversion mutations restores both germline and somatic loss-of-function mutations

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