Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses

Derek N. Bremmer; Joan Miquel Balada-Llasat; Debra A. Goff; Karri A. Bauer

doi:10.1016/j.diagmicrobio.2017.02.019

Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses

Derek N. Bremmer
, Joan Miquel Balada-Llasat
, Debra A. Goff
, Karri A. Bauer

Pathology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We determined the correlation between Etest and BMD MICs with bactericidal activity in MSSA blood isolates. Ceftriaxone was bactericidal in 36% and 9% of isolates exposed to the Etest and BMD MIC, respectively. With the sub-optimal activity of ceftriaxone, the Etest MIC may be a conservative method in identifying clinical utility.

Original language	English
Pages (from-to)	192-194
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	88
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2017.02.019
State	Published - Jun 1 2017

Keywords

Antibiotic susceptibility testing methods
Bacteremia
Ceftriaxone
Staphylococcus aureus
Time-kill curves

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10.1016/j.diagmicrobio.2017.02.019

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title = "Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses",

abstract = "We determined the correlation between Etest and BMD MICs with bactericidal activity in MSSA blood isolates. Ceftriaxone was bactericidal in 36\% and 9\% of isolates exposed to the Etest and BMD MIC, respectively. With the sub-optimal activity of ceftriaxone, the Etest MIC may be a conservative method in identifying clinical utility.",

keywords = "Antibiotic susceptibility testing methods, Bacteremia, Ceftriaxone, Staphylococcus aureus, Time-kill curves",

author = "Bremmer, \{Derek N.\} and Balada-Llasat, \{Joan Miquel\} and Goff, \{Debra A.\} and Bauer, \{Karri A.\}",

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AU - Bremmer, Derek N.

AU - Balada-Llasat, Joan Miquel

AU - Goff, Debra A.

AU - Bauer, Karri A.

PY - 2017/6/1

Y1 - 2017/6/1

N2 - We determined the correlation between Etest and BMD MICs with bactericidal activity in MSSA blood isolates. Ceftriaxone was bactericidal in 36% and 9% of isolates exposed to the Etest and BMD MIC, respectively. With the sub-optimal activity of ceftriaxone, the Etest MIC may be a conservative method in identifying clinical utility.

AB - We determined the correlation between Etest and BMD MICs with bactericidal activity in MSSA blood isolates. Ceftriaxone was bactericidal in 36% and 9% of isolates exposed to the Etest and BMD MIC, respectively. With the sub-optimal activity of ceftriaxone, the Etest MIC may be a conservative method in identifying clinical utility.

KW - Antibiotic susceptibility testing methods

KW - Bacteremia

KW - Ceftriaxone

KW - Staphylococcus aureus

KW - Time-kill curves

UR - https://www.scopus.com/pages/publications/85014776093

U2 - 10.1016/j.diagmicrobio.2017.02.019

DO - 10.1016/j.diagmicrobio.2017.02.019

M3 - Article

C2 - 28291629

AN - SCOPUS:85014776093

SN - 0732-8893

VL - 88

SP - 192

EP - 194

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 2

ER -

Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses

Abstract

Keywords

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