Cytogenetics of acute leukemia

Nyla A. Heerema; Susana Catalina Raimondi

doi:10.1007/978-3-319-64263-5_16

Cytogenetics of acute leukemia

Nyla A. Heerema
, Susana Catalina Raimondi

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Cytogenetic abnormalities are an important factor in patient diagnosis, risk assessment, and treatment in acute leukemia. Characteristic genetic abnormalities are recognized as essential for disease classification and are a significant element of the 2008 World Health Organization (WHO) classification (World health organization classification of tumours of haematopoietic and lymphoid tissues, IARC Press, Lyon, 2008). Some aberrations are involved in the initiation whereas others participate in the progression of different acute leukemias.

Original language	English
Title of host publication	Neoplastic Diseases of the Blood
Publisher	Springer International Publishing
Pages	281-306
Number of pages	26
ISBN (Electronic)	9783319642635
ISBN (Print)	9783319642628
DOIs	https://doi.org/10.1007/978-3-319-64263-5_16
State	Published - Jan 1 2018

Keywords

Chromosome deletions
Chromosome translocations
Core-binding factor
Diploidy
Philadelphia chromosome
Pseudodiploidy

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10.1007/978-3-319-64263-5_16

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abstract = "Cytogenetic abnormalities are an important factor in patient diagnosis, risk assessment, and treatment in acute leukemia. Characteristic genetic abnormalities are recognized as essential for disease classification and are a significant element of the 2008 World Health Organization (WHO) classification (World health organization classification of tumours of haematopoietic and lymphoid tissues, IARC Press, Lyon, 2008). Some aberrations are involved in the initiation whereas others participate in the progression of different acute leukemias.",

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AB - Cytogenetic abnormalities are an important factor in patient diagnosis, risk assessment, and treatment in acute leukemia. Characteristic genetic abnormalities are recognized as essential for disease classification and are a significant element of the 2008 World Health Organization (WHO) classification (World health organization classification of tumours of haematopoietic and lymphoid tissues, IARC Press, Lyon, 2008). Some aberrations are involved in the initiation whereas others participate in the progression of different acute leukemias.

KW - Chromosome deletions

KW - Chromosome translocations

KW - Core-binding factor

KW - Diploidy

KW - Philadelphia chromosome

KW - Pseudodiploidy

UR - https://www.scopus.com/pages/publications/85047039022

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SN - 9783319642628

SP - 281

EP - 306

BT - Neoplastic Diseases of the Blood

PB - Springer International Publishing

ER -

Cytogenetics of acute leukemia

Abstract

Keywords

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