Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase

Keyphrases

• Mammalian Cells 100%
• Sigma Phase 100%
• S-phase Kinase-associated Protein 2 (Skp2) 100%
• Cdt1 100%
• Cyclin 23%
• N-terminus 17%
• Binding Motif 11%
• Threonine 11%
• Phosphorylation 5%
• Overexpression 5%
• Overexpressing 5%
• Cyclin-dependent Kinase 5%
• Mutagenesis Studies 5%
• Cyclin-dependent Kinase 2 (CDK2) 5%
• Dereplication 5%
• Independent Pathway 5%
• F-box Protein 5%
• Delayed Entry 5%
• Phosphopeptides 5%
• Stable Forms 5%

Biochemistry, Genetics and Molecular Biology

• S Phase 100%
• N-Terminus 40%
• Wild Type 20%
• Proliferating Cell Nuclear Antigen 20%
• Threonine 20%
• Cyclin 20%
• Cyclin-Dependent Kinase 10%
• Mutagenesis 10%
• Independent Pathway 10%
• F-Box Protein 10%
• Proteolysis 10%
• Phosphopeptide 10%
• phosphorylation 10%