Detection of protein-protein interactions by proximity-driven S _NAr reactions of lysine-linked fluorophores

Keyphrases

• Protein-protein Interaction 100%
• Lysine 100%
• Fluorophore 100%
• SNAr 100%
• Protein-protein Interface 60%
• Immunoglobulin G 60%
• Gel Electrophoresis 40%
• Lysine Residue 40%
• Fluorinated 40%
• Mass Spectrometry 20%
• Crude Extract 20%
• Cellular Targets 20%
• Binding Partners 20%
• Ribonuclease 20%
• Molecular Probe 20%
• Staphylococcus Aureus 20%
• Interacting Proteins 20%
• Cellular Proteins 20%
• Electrophilic 20%
• Amines 20%
• X-ray Structure 20%
• Protein-modified 20%
• Amino Group 20%
• Bovine Serum Albumin 20%
• Non-specific Binding 20%
• Human HeLa Cells 20%
• Ribonuclease Inhibitor 20%
• Electrophilic Compounds 20%
• Complex Biological Matrices 20%
• Pyronin 20%
• SNAr Mechanism 20%

Biochemistry, Genetics and Molecular Biology

• Protein-Protein Interaction 100%
• Lysine 100%
• Immunoglobulin G 60%
• Electrophilicity 40%
• Gel Electrophoresis 40%
• Staphylococcus Aureus 20%
• Mass Spectrometry 20%
• X Ray 20%
• Extract 20%
• Ribonuclease A 20%
• Bovine Serum Albumin 20%
• Ribonuclease Inhibitor 20%
• Molecular Probe 20%