Abstract
The procedures described in this unit utilize murine models exclusively since murine EAE often results in a relapsing/remitting disease, similar to the early phase of most MS patients. EAE in the Lewis rat is a monophasic illness in which animals experience a single episode of paralysis from which most recover completely. This unit presents two methods for inducing EAE in mice: active induction and adoptive transfer.
| Original language | English |
|---|---|
| Pages (from-to) | Unit9.7 |
| Journal | Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] |
| Volume | Chapter 9 |
| DOIs | |
| State | Published - May 2001 |
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