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Hormonal and gender influences on experimental autoimmune encephalomyelitis

  • Christopher Gilmore
  • , Cris S. Constantinescu
  • , Caroline C. Whitacre

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This chapter highlights the important interactions between the CNS, the endocrine system and the immune system that influence the course of EAE. In particular, we focus on the bi-directional relationship between the hypothalamic-pituitary-adrenal (HPA) axis and EAE, and the influences of gender and sex hormones on EAE.

Original languageEnglish
Title of host publicationExperimental Models of Multiple Sclerosis
PublisherSpringer US
Pages547-560
Number of pages14
ISBN (Electronic)9780387255187
ISBN (Print)0387255176, 9780387255170
DOIs
StatePublished - 2005

Keywords

  • EAE
  • glucocorticoids
  • hypothalamic-pituitary-adrenal axis
  • sex hormones

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