Magnetic separation-assisted diagnosis

Hyeon Choe, Xian Wu, Jacob Strayer, Jenifer Gómez-Pastora, Jeffrey Chalmers

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Accurate disease detection plays a vital role in healthcare systems, by effectively characterizing abnormal biological entities or biomarkers. A promising disease detection technique involves the use of magnetic systems. Magnetic disease detection offers numerous advantages, including enhanced sensitivity, selectivity, and high efficiency. These benefits are achieved through the measurement and characterization of the material’s magnetic properties, as well as the adjustment of the magnetic field gradient and magnitude of the detection device. Labeled techniques evolve around the use of magnetic nanoparticles, which are combined with specific biomolecules before the detection process, resulting in improved sensitivity. Alternatively, the material itself can be directly measured via label-free magnetic detection techniques, thereby minimizing the use of external reagents, and rendering noninvasive systems.

Original languageEnglish
Title of host publicationMagnetic Nanoparticles in Nanomedicine
PublisherElsevier
Pages351-368
Number of pages18
ISBN (Electronic)9780443216688
ISBN (Print)9780443216695
DOIs
StatePublished - Jan 1 2024

Keywords

  • Magnetization
  • disease detection
  • label-free magnetic detection
  • magnetic field
  • magnetic labeled detection
  • magnetic property

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