TY - JOUR
T1 - Mechanisms of contractile-ring assembly in fission yeast and beyond
AU - Laporte, Damien
AU - Zhao, Ran
AU - Wu, Jian Qiu
N1 - Funding Information:
We thank Valerie Coffman and Tom Pollard for critical reading of the manuscript. We regret that we cannot cite all the papers on contractile-ring assembly due to the space limitation. The Wu laboratory is supported by American Heart Association, Great Rivers Affiliate ; Basil O’Connor Starter Scholar Research Award from the March of Dimes Foundation ; and National Institute of Health (NIH) GM086546 .
PY - 2010/12
Y1 - 2010/12
N2 - Most eukaryotes including fungi, amoebas, and animal cells assemble an actin/myosin-based contractile ring during cytokinesis. The majority of proteins implied in ring formation, maturation, and constriction are evolutionarily conserved, suggesting that common mechanisms exist among these divergent eukaryotes. Here, we review the recent advances in positioning and assembly of the actomyosin ring in the fission yeast Schizosaccharomyces pombe, the budding yeast Saccharomyces cerevisiae, and animal cells. In particular, major findings have been made recently in understanding ring formation in genetically tractable S. pombe, revealing a dynamic and robust search, capture, pull, and release mechanism.
AB - Most eukaryotes including fungi, amoebas, and animal cells assemble an actin/myosin-based contractile ring during cytokinesis. The majority of proteins implied in ring formation, maturation, and constriction are evolutionarily conserved, suggesting that common mechanisms exist among these divergent eukaryotes. Here, we review the recent advances in positioning and assembly of the actomyosin ring in the fission yeast Schizosaccharomyces pombe, the budding yeast Saccharomyces cerevisiae, and animal cells. In particular, major findings have been made recently in understanding ring formation in genetically tractable S. pombe, revealing a dynamic and robust search, capture, pull, and release mechanism.
KW - Anillin
KW - Contractile ring
KW - Cytokinesis
KW - Myosin
KW - Node
UR - https://www.scopus.com/pages/publications/78449295414
U2 - 10.1016/j.semcdb.2010.08.004
DO - 10.1016/j.semcdb.2010.08.004
M3 - Review article
C2 - 20708088
AN - SCOPUS:78449295414
SN - 1084-9521
VL - 21
SP - 892
EP - 898
JO - Seminars in Cell and Developmental Biology
JF - Seminars in Cell and Developmental Biology
IS - 9
ER -