Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia

Ana María Ríos; Mónica Fonseca-Aten; Asunción Mejías; Susana Chávez-Bueno; Kathy Katz; Ana María Gómez; George H. McCracken; Octavio Ramilo; R. Doug Hardy

doi:10.1128/AAC.49.9.3970-3973.2005

Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia

Ana María Ríos
, Mónica Fonseca-Aten
, Asunción Mejías
, Susana Chávez-Bueno
, Kathy Katz
, Ana María Gómez
, George H. McCracken
, Octavio Ramilo
, R. Doug Hardy

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.

Original language	English
Pages (from-to)	3970-3973
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	49
Issue number	9
DOIs	https://doi.org/10.1128/AAC.49.9.3970-3973.2005
State	Published - Sep 2005

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10.1128/AAC.49.9.3970-3973.2005

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Ríos, A. M., Fonseca-Aten, M., Mejías, A., Chávez-Bueno, S., Katz, K., Gómez, A. M., McCracken, G. H., Ramilo, O., & Hardy, R. D. (2005). Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia. Antimicrobial agents and chemotherapy, 49(9), 3970-3973. https://doi.org/10.1128/AAC.49.9.3970-3973.2005

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Ríos, AM, Fonseca-Aten, M, Mejías, A, Chávez-Bueno, S, Katz, K, Gómez, AM, McCracken, GH, Ramilo, O & Hardy, RD 2005, 'Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia', Antimicrobial agents and chemotherapy, vol. 49, no. 9, pp. 3970-3973. https://doi.org/10.1128/AAC.49.9.3970-3973.2005

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T1 - Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia

AU - Ríos, Ana María

AU - Fonseca-Aten, Mónica

AU - Mejías, Asunción

AU - Chávez-Bueno, Susana

AU - Katz, Kathy

AU - Gómez, Ana María

AU - McCracken, George H.

AU - Ramilo, Octavio

AU - Hardy, R. Doug

PY - 2005/9

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AB - We evaluated the efficacy of azithromycin therapy given as a single high dose or divided over 5 days for the treatment of mild experimental Mycoplasma pneumoniae pneumonia. Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens.

UR - https://www.scopus.com/pages/publications/24144436945

U2 - 10.1128/AAC.49.9.3970-3973.2005

DO - 10.1128/AAC.49.9.3970-3973.2005

M3 - Article

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AN - SCOPUS:24144436945

SN - 0066-4804

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Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia

Abstract

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