Mitochondria on the move: BMSCs fuel AML energy

Rosa Lapalombella

doi:10.1182/blood-2017-08-798504

Mitochondria on the move: BMSCs fuel AML energy

Rosa Lapalombella

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

In this issue of Blood, Marlein et al¹ identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.

Original language	English
Pages (from-to)	1603-1604
Number of pages	2
Journal	Blood
Volume	130
Issue number	14
DOIs	https://doi.org/10.1182/blood-2017-08-798504
State	Published - Oct 5 2017

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title = "Mitochondria on the move: BMSCs fuel AML energy",

abstract = "In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.",

author = "Rosa Lapalombella",

note = "Publisher Copyright: {\textcopyright} 2017 by The American Society of Hematology.",

year = "2017",

month = oct,

day = "5",

doi = "10.1182/blood-2017-08-798504",

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T1 - Mitochondria on the move

T2 - BMSCs fuel AML energy

AU - Lapalombella, Rosa

PY - 2017/10/5

Y1 - 2017/10/5

N2 - In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.

AB - In this issue of Blood, Marlein et al1 identify a tumor-specific NOX2-dependent transfer of mitochondria from bone marrow stromal cells (BMSCs) to acute myeloid leukemia (AML) cells via AML-derived tunneling nanotubes (see figure), supporting inhibition of NOX2 as a novel therapeutic strategy in AML.

UR - https://www.scopus.com/pages/publications/85030680917

U2 - 10.1182/blood-2017-08-798504

DO - 10.1182/blood-2017-08-798504

M3 - Comment/debate

C2 - 28983016

AN - SCOPUS:85030680917

SN - 0006-4971

VL - 130

SP - 1603

EP - 1604

JO - Blood

JF - Blood

IS - 14

ER -

Mitochondria on the move: BMSCs fuel AML energy

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