No evidence of human leukocyte antigen gene associationwith rheumatic fever among children in samoa

Guliz Erdem; Steven E. Seifried

doi:10.1093/jpids/pit064

No evidence of human leukocyte antigen gene associationwith rheumatic fever among children in samoa

Guliz Erdem
, Steven E. Seifried

Pediatrics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Human leukocyte antigens (HLAs) have been implicated in rheumatic fever pathogenesis. This pilot whole genome association study compares genotypes of Samoan children with rheumatic fever to unaffected siblings and unrelated healthy controls. No risk-related genotypes were associated with HLA genes. Thirteen Regions of Interest were identified as candidates for further study.

Original language	English
Pages (from-to)	71-73
Number of pages	3
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	4
Issue number	1
DOIs	https://doi.org/10.1093/jpids/pit064
State	Published - Mar 2015

Keywords

Genome-wide association study
Polynesian
Rheumatic fever

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10.1093/jpids/pit064

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title = "No evidence of human leukocyte antigen gene associationwith rheumatic fever among children in samoa",

abstract = "Human leukocyte antigens (HLAs) have been implicated in rheumatic fever pathogenesis. This pilot whole genome association study compares genotypes of Samoan children with rheumatic fever to unaffected siblings and unrelated healthy controls. No risk-related genotypes were associated with HLA genes. Thirteen Regions of Interest were identified as candidates for further study.",

keywords = "Genome-wide association study, Polynesian, Rheumatic fever",

author = "Guliz Erdem and Seifried, \{Steven E.\}",

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year = "2015",

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AU - Erdem, Guliz

AU - Seifried, Steven E.

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Y1 - 2015/3

N2 - Human leukocyte antigens (HLAs) have been implicated in rheumatic fever pathogenesis. This pilot whole genome association study compares genotypes of Samoan children with rheumatic fever to unaffected siblings and unrelated healthy controls. No risk-related genotypes were associated with HLA genes. Thirteen Regions of Interest were identified as candidates for further study.

AB - Human leukocyte antigens (HLAs) have been implicated in rheumatic fever pathogenesis. This pilot whole genome association study compares genotypes of Samoan children with rheumatic fever to unaffected siblings and unrelated healthy controls. No risk-related genotypes were associated with HLA genes. Thirteen Regions of Interest were identified as candidates for further study.

KW - Genome-wide association study

KW - Polynesian

KW - Rheumatic fever

UR - https://www.scopus.com/pages/publications/85006230917

U2 - 10.1093/jpids/pit064

DO - 10.1093/jpids/pit064

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AN - SCOPUS:85006230917

SN - 2048-7193

VL - 4

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JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

IS - 1

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No evidence of human leukocyte antigen gene associationwith rheumatic fever among children in samoa

Abstract

Keywords

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