Periodic lateralized epileptiform discharges in multiple sclerosis

David R. Chabolla; J Layne Moore; Barbara F. Westmoreland

doi:10.1016/0013-4694(95)00211-1

Periodic lateralized epileptiform discharges in multiple sclerosis

David R. Chabolla
, J Layne Moore
, Barbara F. Westmoreland

Neurology

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

We report an unusual cause of periodic lateralized epileptiform discharges (PLEDs) in a young man with a long history of multiple sclerosis. Two exacerbations of multiple sclerosis, 3 years apart, were complicated by complex partial status epilepticus. After each episode, serial electroencephalograms revealed PLEDs (right frontal PLEDs in the first episode and right frontotemporal and bifrontal PLEDs in the second one), which resolved within 2 weeks. With the first episode, magnetic resonance imaging revealed an enhancing white matter lesion in the right frontal area, which improved after 3 weeks. We concluded that in each instance an exacerbation of multiple sclerosis caused the seizures.

Original language	English
Pages (from-to)	5-8
Number of pages	4
Journal	Electroencephalography and Clinical Neurophysiology
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/0013-4694(95)00211-1
State	Published - Jan 1 1996

Keywords

Case history
EEG
Multiple sclerosis
Periodic lateralized epileptiform discharge (PLED)
Seizures

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10.1016/0013-4694(95)00211-1

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title = "Periodic lateralized epileptiform discharges in multiple sclerosis",

abstract = "We report an unusual cause of periodic lateralized epileptiform discharges (PLEDs) in a young man with a long history of multiple sclerosis. Two exacerbations of multiple sclerosis, 3 years apart, were complicated by complex partial status epilepticus. After each episode, serial electroencephalograms revealed PLEDs (right frontal PLEDs in the first episode and right frontotemporal and bifrontal PLEDs in the second one), which resolved within 2 weeks. With the first episode, magnetic resonance imaging revealed an enhancing white matter lesion in the right frontal area, which improved after 3 weeks. We concluded that in each instance an exacerbation of multiple sclerosis caused the seizures.",

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AU - Moore, J Layne

AU - Westmoreland, Barbara F.

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N2 - We report an unusual cause of periodic lateralized epileptiform discharges (PLEDs) in a young man with a long history of multiple sclerosis. Two exacerbations of multiple sclerosis, 3 years apart, were complicated by complex partial status epilepticus. After each episode, serial electroencephalograms revealed PLEDs (right frontal PLEDs in the first episode and right frontotemporal and bifrontal PLEDs in the second one), which resolved within 2 weeks. With the first episode, magnetic resonance imaging revealed an enhancing white matter lesion in the right frontal area, which improved after 3 weeks. We concluded that in each instance an exacerbation of multiple sclerosis caused the seizures.

AB - We report an unusual cause of periodic lateralized epileptiform discharges (PLEDs) in a young man with a long history of multiple sclerosis. Two exacerbations of multiple sclerosis, 3 years apart, were complicated by complex partial status epilepticus. After each episode, serial electroencephalograms revealed PLEDs (right frontal PLEDs in the first episode and right frontotemporal and bifrontal PLEDs in the second one), which resolved within 2 weeks. With the first episode, magnetic resonance imaging revealed an enhancing white matter lesion in the right frontal area, which improved after 3 weeks. We concluded that in each instance an exacerbation of multiple sclerosis caused the seizures.

KW - Case history

KW - EEG

KW - Multiple sclerosis

KW - Periodic lateralized epileptiform discharge (PLED)

KW - Seizures

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JO - Electroencephalography and Clinical Neurophysiology

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Periodic lateralized epileptiform discharges in multiple sclerosis

Abstract

Keywords

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