Persistent interactions between the two transmembrane clusters dictate the targeting and functional assembly of adenylyl cyclase

Keyphrases

• Adenylyl Cyclase 100%
• Transmembrane 100%
• Functional Assembly 100%
• Plasma Membrane 66%
• Transmembrane Domain 66%
• Catalytic Domain 66%
• Transmembrane Segment 66%
• Co-immunoprecipitation (co-IP) 33%
• Living Cells 33%
• Microscopy 33%
• Cystic Fibrosis Transmembrane Conductance Regulator 33%
• Functional Assay 33%
• Intact Cells 33%
• Complex Structure 33%
• Tight 33%
• Single-molecule Fluorescence Resonance Energy Transfer (smFRET) 33%
• N-terminus 33%
• Cassette 33%
• P-glycoprotein (P-gp) 33%
• ATP Binding 33%
• K+ Channels 33%
• ATP-binding Cassette Transporter A1 (ABCA1) 33%
• Cytoplasmic Loop 33%
• Extracellular Loop 33%
• Adenylyl Cyclase Activity 33%
• Glycosylation Site 33%
• Cell Fluorescence 33%
• Transporter Family 33%

Biochemistry, Genetics and Molecular Biology

• Adenylate Cyclase 100%
• Enzyme Active Site 66%
• Cell Membrane 66%
• Adenosine Triphosphate 66%
• Transmembrane Domain 66%
• Enzyme 33%
• N-Terminus 33%
• Fluorescence Resonance Energy Transfer 33%
• Cystic Fibrosis 33%
• Crystal Structure 33%
• Glycosylation 33%
• Potassium Channel 33%
• Cooperation 33%
• P-Glycoprotein 33%
• ATP-binding Cassette Transporter 33%
• ABC Transporter 33%