TY - JOUR
T1 - Pharmacogenomic testing
T2 - Relevance in medical practice: Why drugs work in some patients but not in others
AU - Kitzmiller, Joseph P.
AU - Groen, David K.
AU - Phelps, Mitch A.
AU - Sadee, Wolfgang
PY - 2011/4
Y1 - 2011/4
N2 - Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine.
AB - Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine.
UR - http://www.scopus.com/inward/record.url?scp=79954514722&partnerID=8YFLogxK
U2 - 10.3949/ccjm.78a.10145
DO - 10.3949/ccjm.78a.10145
M3 - Review article
C2 - 21460130
AN - SCOPUS:79954514722
SN - 0891-1150
VL - 78
SP - 243
EP - 257
JO - Cleveland Clinic Journal of Medicine
JF - Cleveland Clinic Journal of Medicine
IS - 4
ER -