Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8

H. Becker; K. Maharry; K. Mrózek; S. Volinia; A. K. Eisfeld; M. D. Radmacher; J. Kohlschmidt; K. H. Metzeler; S. Schwind; S. P. Whitman; J. H. Mendler; Y. Z. Wu; D. Nicolet; P. Paschka; B. L. Powell; T. H. Carter; M. Wetzler; J. E. Kolitz; A. J. Carroll; M. R. Baer; M. A. Caligiuri; R. M. Stone; G. Marcucci; C. D. Bloomfield

doi:10.1038/leu.2014.114

Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8

H. Becker
, K. Maharry
, K. Mrózek
, S. Volinia
, A. K. Eisfeld
, M. D. Radmacher
, J. Kohlschmidt
, K. H. Metzeler
, S. Schwind
, S. P. Whitman
, J. H. Mendler
, Y. Z. Wu
, D. Nicolet
, P. Paschka
, B. L. Powell
, T. H. Carter
, M. Wetzler
, J. E. Kolitz
, A. J. Carroll
, M. R. Baer

M. A. Caligiuri, R. M. Stone, G. Marcucci, C. D. Bloomfield

Research output: Contribution to journal › Letter › peer-review

29 Scopus citations

Original language	English
Pages (from-to)	1754-1758
Number of pages	5
Journal	Leukemia
Volume	28
Issue number	8
DOIs	https://doi.org/10.1038/leu.2014.114
State	Published - Aug 2014

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10.1038/leu.2014.114

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Becker, H., Maharry, K., Mrózek, K., Volinia, S., Eisfeld, A. K., Radmacher, M. D., Kohlschmidt, J., Metzeler, K. H., Schwind, S., Whitman, S. P., Mendler, J. H., Wu, Y. Z., Nicolet, D., Paschka, P., Powell, B. L., Carter, T. H., Wetzler, M., Kolitz, J. E., Carroll, A. J., ... Bloomfield, C. D. (2014). Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8. Leukemia, 28(8), 1754-1758. https://doi.org/10.1038/leu.2014.114

@article{92fbc25f34824c718c4f0c46a766e53a,

title = "Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8",

author = "H. Becker and K. Maharry and K. Mr{\'o}zek and S. Volinia and Eisfeld, \{A. K.\} and Radmacher, \{M. D.\} and J. Kohlschmidt and Metzeler, \{K. H.\} and S. Schwind and Whitman, \{S. P.\} and Mendler, \{J. H.\} and Wu, \{Y. Z.\} and D. Nicolet and P. Paschka and Powell, \{B. L.\} and Carter, \{T. H.\} and M. Wetzler and Kolitz, \{J. E.\} and Carroll, \{A. J.\} and Baer, \{M. R.\} and Caligiuri, \{M. A.\} and Stone, \{R. M.\} and G. Marcucci and Bloomfield, \{C. D.\}",

note = "Funding Information: The Cancer and Leukemia Group B (CALGB) institutions, principal investigators and cytogeneticists participating in this study are provided in the Supplementary Information. The research was supported in part by National Cancer Institute, Bethesda, MD grants CA101140, CA140158, CA114725, CA129657, CA16058, CA77658, The Coleman Leukemia Research Foundation, the Deutsche Krebshilfe—Dr Mildred Scheel Foundation (to HB) and the Research Committee of the University Freiburg, Germany (to HB), the Pelotonia Fellowship Program (to A-KE), and the Conquer Cancer Foundation (to JHM). The research for CALGB 8461, 20202 and 9665 (Alliance) was supported, in part, by grants from the National Cancer Institute (CA31946) to the Alliance for Clinical Trials in Oncology (Monica M Bertagnolli, Chair) and to the Alliance Statistics and Data Center (Daniel J Sargent, CA33601). The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute. We thank Donna Bucci and the CALGB Leukemia Tissue Bank at The Ohio State University Comprehensive Cancer Center, Columbus, OH, for sample processing and storage services, Colin G Edwards, PhD, Lisa J Sterling and Christine Finks for data management, and Dean Margeson and Kelsi B Holland for assistance in the statistical analyses. Moreover, we thank Stephan M Tanner, PhD and Albert de la Chapelle, MD, PhD for scientific discussions.",

year = "2014",

month = aug,

doi = "10.1038/leu.2014.114",

language = "English",

volume = "28",

pages = "1754--1758",

journal = "Leukemia",

issn = "0887-6924",

number = "8",

}

Becker, H, Maharry, K, Mrózek, K, Volinia, S, Eisfeld, AK, Radmacher, MD, Kohlschmidt, J, Metzeler, KH, Schwind, S, Whitman, SP, Mendler, JH, Wu, YZ, Nicolet, D, Paschka, P, Powell, BL, Carter, TH, Wetzler, M, Kolitz, JE, Carroll, AJ, Baer, MR, Caligiuri, MA, Stone, RM, Marcucci, G & Bloomfield, CD 2014, 'Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8', Leukemia, vol. 28, no. 8, pp. 1754-1758. https://doi.org/10.1038/leu.2014.114

TY - JOUR

T1 - Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8

AU - Becker, H.

AU - Maharry, K.

AU - Mrózek, K.

AU - Volinia, S.

AU - Eisfeld, A. K.

AU - Radmacher, M. D.

AU - Kohlschmidt, J.

AU - Metzeler, K. H.

AU - Schwind, S.

AU - Whitman, S. P.

AU - Mendler, J. H.

AU - Wu, Y. Z.

AU - Nicolet, D.

AU - Paschka, P.

AU - Powell, B. L.

AU - Carter, T. H.

AU - Wetzler, M.

AU - Kolitz, J. E.

AU - Carroll, A. J.

AU - Baer, M. R.

AU - Caligiuri, M. A.

AU - Stone, R. M.

AU - Marcucci, G.

AU - Bloomfield, C. D.

N1 - Funding Information: The Cancer and Leukemia Group B (CALGB) institutions, principal investigators and cytogeneticists participating in this study are provided in the Supplementary Information. The research was supported in part by National Cancer Institute, Bethesda, MD grants CA101140, CA140158, CA114725, CA129657, CA16058, CA77658, The Coleman Leukemia Research Foundation, the Deutsche Krebshilfe—Dr Mildred Scheel Foundation (to HB) and the Research Committee of the University Freiburg, Germany (to HB), the Pelotonia Fellowship Program (to A-KE), and the Conquer Cancer Foundation (to JHM). The research for CALGB 8461, 20202 and 9665 (Alliance) was supported, in part, by grants from the National Cancer Institute (CA31946) to the Alliance for Clinical Trials in Oncology (Monica M Bertagnolli, Chair) and to the Alliance Statistics and Data Center (Daniel J Sargent, CA33601). The content of this manuscript is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute. We thank Donna Bucci and the CALGB Leukemia Tissue Bank at The Ohio State University Comprehensive Cancer Center, Columbus, OH, for sample processing and storage services, Colin G Edwards, PhD, Lisa J Sterling and Christine Finks for data management, and Dean Margeson and Kelsi B Holland for assistance in the statistical analyses. Moreover, we thank Stephan M Tanner, PhD and Albert de la Chapelle, MD, PhD for scientific discussions.

PY - 2014/8

Y1 - 2014/8

UR - https://www.scopus.com/pages/publications/84905695377

U2 - 10.1038/leu.2014.114

DO - 10.1038/leu.2014.114

M3 - Letter

C2 - 24651097

AN - SCOPUS:84905695377

SN - 0887-6924

VL - 28

SP - 1754

EP - 1758

JO - Leukemia

JF - Leukemia

IS - 8

ER -

Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8

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