Radioimmunoguided Surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future

Duxin Sun; Mark Bloomston; George Hinkle; Osama Habib Al-Saif; Nathan C. Hall; Stephen P. Povoski; Mark W. Arnold; Edward W. Martin

doi:10.1002/jso.20869

Radioimmunoguided Surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future

Duxin Sun, Mark Bloomston, George Hinkle, Osama Habib Al-Saif, Nathan C. Hall, Stephen P. Povoski, Mark W. Arnold, Edward W. Martin

Research output: Contribution to journal › Review article › peer-review

43 Scopus citations

Abstract

¹²⁵I-labeled anti-TAG-72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle ¹²⁵I-labeled materials. PET/CT image-guided surgery utilizes ¹⁸FDG to monitor the biochemical activity of the tumor and to integrate pre- and postoperative imaging for complete tumor removal. PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors.

Original language	English
Pages (from-to)	297-308
Number of pages	12
Journal	Journal of surgical oncology
Volume	96
Issue number	4
DOIs	https://doi.org/10.1002/jso.20869
State	Published - Sep 15 2007

Keywords

CC49
PET
RIGS
Surgery

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10.1002/jso.20869

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title = "Radioimmunoguided Surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future",

abstract = "125I-labeled anti-TAG-72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle 125I-labeled materials. PET/CT image-guided surgery utilizes 18FDG to monitor the biochemical activity of the tumor and to integrate pre- and postoperative imaging for complete tumor removal. PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors.",

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AU - Bloomston, Mark

AU - Hinkle, George

AU - Al-Saif, Osama Habib

AU - Hall, Nathan C.

AU - Povoski, Stephen P.

AU - Arnold, Mark W.

AU - Martin, Edward W.

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AB - 125I-labeled anti-TAG-72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle 125I-labeled materials. PET/CT image-guided surgery utilizes 18FDG to monitor the biochemical activity of the tumor and to integrate pre- and postoperative imaging for complete tumor removal. PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors.

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KW - Surgery

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Radioimmunoguided Surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future

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