Keyphrases
Mast Cell Activation
100%
Structural Requirements
100%
Calcium Mobilization
100%
BTP2
100%
Pyrazole Derivatives
100%
Mast Cells
50%
Trifluoromethyl
50%
Methyl
33%
FcRI
33%
C-3 Position
33%
Bone Marrow-derived Mast Cell
33%
Pyrazole
33%
Immune Function
16%
Interleukin-2
16%
Cell Release
16%
Mitogen-activated Protein Kinase
16%
Phosphorylation
16%
Allergen
16%
Allergic Inflammation
16%
Tumor Necrosis Factor-α
16%
Tyrosine Phosphorylation
16%
Histamine
16%
Interleukin-4 (IL-4)
16%
Degranulation
16%
Interleukin-6
16%
Granulocyte Colony-stimulating Factor (G-CSF)
16%
Cell Response
16%
Cellular Proteins
16%
Allergic Reaction
16%
ERK2
16%
Intracellular Ca2+
16%
Ca2+ Influx
16%
Interleukin-13 (IL-13)
16%
High-affinity Receptor
16%
Related Compounds
16%
Structure-activity Relationship Studies
16%
Carboxamide
16%
Phenyl
16%
Interleukin-3
16%
Immediate Hypersensitivity
16%
Pyrazol
16%
Nuclear Factor of Activated T Cells
16%
Cell Translocation
16%
Basophils
16%
RBL-2H3
16%
Histamine Release
16%
1,2,3-thiadiazole
16%
C5 Position
16%
Pyrazole Moiety
16%
Trifluoromethyl Group
16%
4-methyl-1
16%
Immunology and Microbiology
Mast Cell
100%
Cell Activation
100%
Calcium Mobilization
100%
Immunoglobulin E
50%
Histamine Release
50%
Bone Marrow Derived Mast Cell
50%
Cytokine
25%
Allergic Inflammation
25%
Allergen
25%
Protein Phosphorylation
25%
Secretion (Process)
25%
Mediator
25%
Degranulation
25%
Mitogen
25%
Interleukin 6
25%
Granulocyte Macrophage Colony-Stimulating Factor
25%
Immunity
25%
Interleukin 2
25%
Hypersensitive Response
25%
Immediate Type Hypersensitivity
25%
Structure Activity Relation
25%
Tumor Necrosis Factor
25%
Interleukin 4
25%
Interleukin 13
25%
Receptor Affinity
25%
Transcription Factor NFAT
25%
Interleukin 3
25%
RBL-2H3 Cell Line
25%
Basophil
25%
Pharmacology, Toxicology and Pharmaceutical Science
Pyrazole
100%
Pyrazole Derivative
100%
Immunoglobulin E
66%
Histamine
66%
Structure Activity Relationship
33%
Cytokine
33%
Receptor
33%
Inflammation
33%
Mitogen Activated Protein Kinase
33%
Tumor Necrosis Factor
33%
Interleukin 6
33%
Cell Protein
33%
Immediate Type Hypersensitivity
33%
Interleukin 2
33%
Carboxamide
33%
Allergic Reaction
33%
Interleukin 13
33%
Transcription Factor NFAT
33%
Granulocyte Macrophage Colony Stimulating Factor
33%
Allergen
33%
Interleukin 4
33%
Interleukin 3
33%
Thiadiazoles
33%