Abstract
The elderly are susceptible to infection with the bacterial pathogen Mycobacterium tuberculosis, and to the development of active TB disease. In this review we utilize experimental data from animal models to discuss the concept that age-associated changes in immune function are a critical parameter that contributes to the increased susceptibility of the elderly to M. tuberculosis infection.
| Original language | English |
|---|---|
| Pages (from-to) | 73-82 |
| Number of pages | 10 |
| Journal | Open Longevity Science |
| Volume | 6 |
| DOIs | |
| State | Published - 2012 |
Keywords
- Aging
- Immunology
- Tuberculosis
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