Projects per year
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Dive into the research topics where Alex Sparreboom is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 5 Finished
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Therapeutic Strategies to Mitigate Toxicities of Anthracycline-Based Therapeutics
Sparreboom, A. (PI), Addison, D. (CoPI) & Baker, S. (CoPI)
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
01/1/24 → 12/31/24
Project: Research
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(9) Therapeutic strategies to mitigate toxicities of platinum-based therapeutics
Sparreboom, A. (PI) & Pabla, N. (CoPI)
04/3/17 → 03/31/18
Project: Research
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Solute Carriers and Oxaliplatin Neurotoxicity
Sparreboom, A. (PI) & Sparreboom, A. (CoPI)
04/1/15 → 03/31/20
Project: Research
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Organic cation transporter 2 and cisplatin nephrotoxicity
Sparreboom, A. (PI)
07/12/10 → 04/30/16
Project: Research
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PHARMACODYNAMICS OF ANTILEUKEMIC AGENTS IN CHILDREN
Sparreboom, A. (PI) & Evans, W. E. (CoPI)
06/1/98 → 05/31/04
Project: Research
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Resazurin dye is an in vivo sensor of kidney tubular function
Martinez, S. A., Karel, I. Z., Silvaroli, J. A., Ahmed, E., Kim, J. Y., Stayton, A., Patel, P. S., Afjal, M. A., Horton, T., Bohmer, M., Vanichapol, T., Sander, V., Andrade, G. M., Allison, C. V., Mondal, M., Thorson, V. C., Partey, A., Nimkar, K., Williams, V. & Quimby, J. & 16 others, , Mar 2025, In: Kidney International. 107, 3, p. 508-520 13 p.Research output: Contribution to journal › Article › peer-review
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Darolutamide does not interfere with OATP-mediated uptake of docetaxel
Buck, S. A. J., Talebi, Z., Drabison, T., Jin, Y., Gibson, A. A., Hu, P., de Bruijn, P., de Ridder, C. M. A., Stuurman, D., Hu, S., van Weerden, W. M., Koolen, S. L. W., de Wit, R., Sparreboom, A., Mathijssen, R. H. J. & Eisenmann, E. D., Jul 15 2024, In: International Journal of Cancer. 155, 2, p. 314-323 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Membrane transporters in drug development and as determinants of precision medicine
Galetin, A., Brouwer, K. L. R., Tweedie, D., Yoshida, K., Sjöstedt, N., Aleksunes, L., Chu, X., Evers, R., Hafey, M. J., Lai, Y., Matsson, P., Riselli, A., Shen, H., Sparreboom, A., Varma, M. V. S., Yang, J., Yang, X., Yee, S. W., Zamek-Gliszczynski, M. J. & Zhang, L. & 1 others, , Apr 2024, In: Nature Reviews Drug Discovery. 23, 4, p. 255-280 26 p.Research output: Contribution to journal › Review article › peer-review
61 Scopus citations -
Pharmacokinetic assessment of low dose decitabine in combination therapies: Development and validation of a sensitive UHPLC-MS/MS method for murine plasma analysis
Anabtawi, N., Drabison, T., Jin, Y., Eisenmann, E. D., Sparreboom, A., Govindarajan, R., Baker, S. D. & Ahmed, E., Jul 15 2024, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1242, 124209.Research output: Contribution to journal › Article › peer-review
Open Access -
Proton Pump Inhibitors May Cause a Decline in eGFR by Inhibiting Organic Cation Transporter 2-Dependent Creatinine Secretion
Pabla, N. S. & Sparreboom, A., Nov 1 2024, In: Journal of the American Society of Nephrology. 35, 11, p. 1613 1 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations