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Dive into the research topics where Dawn S. Chandler is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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A new mouse model for testing splice-switching therapies in IGF-driven cancers
03/16/21 → 02/28/23
Project: Research
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Oncogenic fusion gene FAX-FKHR in driving metabolic reprogramming in alveolar rhabdomyosarcoma
04/1/19 → 02/28/21
Project: Research
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Targeting insulin receptor splicing for treatment of rhabdomyosarcoma
06/1/16 → 05/31/20
Project: Research
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Alternatively Spliced Landscape of PPARγ mRNA in Podocytes Is Distinct from Adipose Tissue
Bryant, C., Webb, A., Banks, A. S., Chandler, D., Govindarajan, R. & Agrawal, S., Nov 2022, In: Cells. 11, 21, 3455.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Alternative RNA splicing defects in pediatric cancers: new insights in tumorigenesis and potential therapeutic vulnerabilities
Venkataramany, A. S., Schieffer, K. M., Lee, K., Cottrell, C. E., Wang, P. Y., Mardis, E. R., Cripe, T. P. & Chandler, D. S., Jun 2022, In: Annals of Oncology. 33, 6, p. 578-592 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA
Dominguez, C. E., Cunningham, D., Venkataramany, A. S. & Chandler, D. S., Feb 2022, In: Human Genetics. 141, 2, p. 239-256 18 p.Research output: Contribution to journal › Article › peer-review
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Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics
Cripe, T. P., Hutzen, B., Currier, M. A., Chen, C. Y., Glaspell, A. M., Sullivan, G. C., Hurley, J. M., Deighen, M. R., Venkataramany, A. S., Mo, X., Stanek, J. R., Miller, A. R., Wijeratne, S., Magrini, V., Mardis, E. R., Mendell, J. R., Chandler, D. S. & Wang, P. Y., Jul 2022, In: Science Advances. 8, 28, eabm1890.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Splice-switching of the insulin receptor pre-mRNA alleviates tumorigenic hallmarks in rhabdomyosarcoma
Khurshid, S., Montes, M., Comiskey, D. F., Shane, B., Matsa, E., Jung, F., Brown, C., Bid, H. K., Wang, R., Houghton, P. J., Roberts, R., Rigo, F. & Chandler, D., Dec 2022, In: npj Precision Oncology. 6, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations