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Dive into the research topics where Hazem Ghoneim is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease
Daily, K. P., Badr, A., Eltobgy, M., Estfanous, S., Whitham, O., Tan, M. H., Carafice, C., Krause, K., McNamara, A., Hamilton, K., Houle, S., Gupta, S., Gupta, G. A., Madhu, S., Fitzgerald, J., Saadey, A. A., Laster, B., Yan, P., Webb, A., Zhang, X., & 4 others , Dec 2024, In: Alzheimer's Research and Therapy. 16, 1, 29.Research output: Contribution to journal › Article › peer-review
Open Access -
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
Read, K. A., Jones, D. M., Pokhrel, S., Hales, E. D. S., Varkey, A., Tuazon, J. A., Eisele, C. D., Abdouni, O., Saadey, A., Leonard, M. R., Warren, R. T., Powell, M. D., Boss, J. M., Hemann, E. A., Yount, J. S., Xin, G., Ghoneim, H. E., Lio, C. W. J., Freud, A. G., Collins, P. L., & 1 others , Dec 2023, In: Nature Communications. 14, 1, 1652.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Functional T cells are capable of supernumerary cell division and longevity
Soerens, A. G., Künzli, M., Quarnstrom, C. F., Scott, M. C., Swanson, L., Locquiao, J., Ghoneim, H. E., Zehn, D., Youngblood, B., Vezys, V. & Masopust, D., Feb 23 2023, In: Nature. 614, 7949, p. 762-766 5 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Rebalancing TGFβ1/BMP signals in exhausted T cells unlocks responsiveness to immune checkpoint blockade therapy
Saadey, A. A., Yousif, A., Osborne, N., Shahinfar, R., Chen, Y. L., Laster, B., Rajeev, M., Bauman, P., Webb, A. & Ghoneim, H. E., Feb 2023, In: Nature Immunology. 24, 2, p. 280-294 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Epigenetic remodeling by vitamin C potentiates plasma cell differentiation
Chen, H. Y., Almonte-Loya, A., Lay, F. Y., Hsu, M., Johnson, E., González-Avalos, E., Yin, J., Bruno, R. S., Ma, Q., Ghoneim, H. E., Wozniak, D. J., Harrison, F. E. & Lio, C. W. J., 2022, In: eLife. 11, e73754.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations