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Dive into the research topics where Jacob Yount is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Mechanisms of lung and cardiac pathology in SARS-CoV-2 infections
National Heart, Lung, and Blood Institute
04/15/23 → 01/31/25
Project: Research
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Mechanistic characterization of a new master regulator of cardiac virus infections
Accornero, F. & Yount, J.
National Heart, Lung, and Blood Institute
09/8/20 → 07/31/24
Project: Research
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Mechanisms of innate resistance to virus infections
National Institute of Allergy and Infectious Diseases
02/1/17 → 01/31/25
Project: Research
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Inhibition of cell-to-cell fusion by interferon-induced proteins
National Institute of Allergy and Infectious Diseases
06/1/19 → 05/31/21
Project: Research
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Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos
Jones, D. M., Tuazon, J. A., Read, K. A., Leonard, M. R., Pokhrel, S., Sreekumar, B. K., Warren, R. T., Yount, J. S., Collins, P. L. & Oestreich, K. J., Apr 1 2024, In: Journal of Immunology. 212, 7, p. 1129-1141 13 p.Research output: Contribution to journal › Article › peer-review
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Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation
Speaks, S., McFadden, M. I., Zani, A., Solstad, A., Leumi, S., Roettger, J. E., Kenney, A. D., Bone, H., Zhang, L., Denz, P. J., Eddy, A. C., Amer, A. O., Robinson, R. T., Cai, C., Ma, J., Hemann, E. A., Forero, A. & Yount, J. S., Dec 2024, In: Nature Communications. 15, 1, 2751.Research output: Contribution to journal › Article › peer-review
Open Access -
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
Read, K. A., Jones, D. M., Pokhrel, S., Hales, E. D. S., Varkey, A., Tuazon, J. A., Eisele, C. D., Abdouni, O., Saadey, A., Leonard, M. R., Warren, R. T., Powell, M. D., Boss, J. M., Hemann, E. A., Yount, J. S., Xin, G., Ghoneim, H. E., Lio, C. W. J., Freud, A. G., Collins, P. L., & 1 others , Dec 2023, In: Nature Communications. 14, 1, 1652.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
A next-generation intranasal trivalent MMS vaccine induces durable and broad protection against SARS-CoV-2 variants of concern
Xu, J., Zhang, Y., Qu, P., Shamseldin, M. M., Yoo, S. J., Misny, J., Thongpan, I., Mahesh, K. C., Hall, J. M., Evans, J. P., Eltobgy, M., Lu, M., Ye, C., Chamblee, M., Liang, X., Martinez-Sobrido, L., Amer, A. O., Yount, J. S., Boyaka, P. N., Peeples, M. E., & 3 others , 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 41, e2220403120.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2
Bednash, J. S., Johns, F., Farkas, D., Elhance, A., Adair, J., Cress, K., Yount, J. S., Kenney, A. D., Londino, J. D. & Mallampalli, R. K., May 2023, In: American journal of respiratory cell and molecular biology. 68, 5, p. 566-576 11 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations